Ngati vuto la magazi losagwira bwino ntchito kwa wodwalayo limayambitsa kutuluka magazi, likhoza kuchitika chifukwa cha kuchepa kwa magazi oundana. Kuyezetsa magazi kofunikira ndikofunikira. N'zoonekeratu kuti magazi amayamba chifukwa cha kusowa kwa magazi oundana kapena zinthu zina zotsutsana ndi magazi. Malinga ndi chifukwa chake, onjezerani magazi ogwirizana ndi magazi kapena plasma yatsopano. Kukhalapo kwa magazi oundana ambiri kungathandize kuletsa kutuluka magazi. Mwachipatala, zitha kuzindikirika ngati magazi ogwirizana ndi magazi amkati ndi kunja kwa magazi oundana a magazi achepa kapena ali ndi vuto losagwira ntchito, ndikuwona ngati magazi osagwirizana ndi magazi amayamba chifukwa cha kusowa kwa magazi oundana kapena ntchito ya magazi oundana, makamaka kuphatikizapo zinthu zotsatirazi:

1. Njira yosazolowereka yolumikizira ziwalo zamkati: Chinthu chachikulu chomwe chimakhudza njira yolumikizira ziwalo zamkati ndi APTT. Ngati APTT yatalikira, zikutanthauza kuti pali zinthu zosazolowereka zolumikizira ziwalo zamkati, monga chinthu 12, chinthu 9, chinthu 8, ndi njira yodziwika bwino 10. Kusowa kwa zinthu kungayambitse zizindikiro za kutuluka magazi mwa odwala;

2. Njira yosazolowereka yolumikizirana kwa magazi kunja: ngati PT yatalikirapo, zitha kudziwika kuti chinthu cha minofu, chinthu chachisanu ndi chimodzi ndi chinthu chachisanu ndi chimodzi (factor 10) m'njira yodziwika bwino zitha kukhala zachilendo, ndiko kuti, kuchepa kwa chiwerengerocho kumabweretsa nthawi yayitali yolumikizirana kwa magazi ndipo kumayambitsa kutuluka magazi mwa wodwalayo.