Kiti Yogwiritsira Ntchito Nthawi Yochepa ya Thromboplastin (APTT)

Kuyeza kwa APTT ndi njira yowunikira yomwe imagwiritsidwa ntchito kwambiri poyesa magazi kuti iwonetse momwe magazi amagwirira ntchito m'thupi. Imagwiritsidwa ntchito kuzindikira zolakwika za magazi m'thupi ndi zoletsa zina zokhudzana nazo komanso kuwona momwe magazi amagwirira ntchito polimbana ndi protein C. Imagwiritsidwa ntchito m'njira zosiyanasiyana poyang'anira, kuyang'anira chithandizo cha heparin, kuzindikira msanga kwa magazi m'mitsempha (DIC), komanso kufufuza magazi asanayambe opaleshoni.

Kufunika kwachipatala:

APTT ndi chizindikiro cha ntchito yolimbitsa magazi chomwe chimasonyeza njira yolimbitsa magazi ya endogenous coagulation, makamaka ntchito yonse ya zinthu zolimbitsa magazi mu gawo loyamba. Chimagwiritsidwa ntchito kwambiri pofufuza ndi kuzindikira zolakwika za zinthu zolimbitsa magazi mu njira yolimbitsa magazi, monga factor Ⅺ , Ⅷ, Ⅸ, chingagwiritsidwenso ntchito poyesa matenda otuluka magazi ndikuwunika chithandizo cha heparin choletsa magazi kulowa m'magazi m'ma laboratories.

1. Kutalika: kungawonekere mu hemophilia A, hemophilia B, matenda a chiwindi, matenda oletsa kutsekeka kwa matumbo, mankhwala oletsa kutsekeka kwa magazi m'kamwa, kutsekeka kwa magazi m'mitsempha, kuchepa kwa magazi m'thupi pang'ono; FXI, FXII kusowa; magazi Zinthu zoletsa kutsekeka kwa magazi (zoletsa kutsekeka kwa magazi, mankhwala oletsa kutsekeka kwa magazi m'mitsempha, warfarin kapena heparin) zinawonjezeka; magazi ambiri osungidwa anaikidwa.

2. Kufupikitsa: Kungaonekere mu mkhalidwe wokhuthala kwambiri, matenda a thromboembolic, ndi zina zotero.

Mndandanda wa mtengo wabwinobwino

Mtengo wabwinobwino wa nthawi yogwiritsidwa ntchito ya thromboplastin (APTT): masekondi 27-45.

Kusamalitsa

1. Pewani hemolysis ya chitsanzo. Chitsanzo choyeretsedwa ndi hemolysis chili ndi ma phospholipids omwe amatulutsidwa ndi kuphulika kwa nembanemba ya maselo ofiira a magazi okhwima, zomwe zimapangitsa APTT kukhala yotsika kuposa mtengo woyezedwa wa chitsanzo choyeretsedwa ndi hemolysis.

2. Odwala sayenera kuchita zinthu zolimbitsa thupi mkati mwa mphindi 30 asanalandire magazi.

3. Mukatenga chitsanzo cha magazi, gwedezani pang'onopang'ono chubu choyesera chomwe chili ndi chitsanzo cha magazi katatu mpaka kasanu kuti muphatikize mokwanira chitsanzo cha magazi ndi mankhwala oletsa magazi kulowa m'chubu choyesera.

4. Zitsanzo za magazi ziyenera kutumizidwa kuti zikaunikidwe mwachangu momwe zingathere.