Kei roto i te toto tangata ngā pūnaha toto totoka me ngā pūnaha ārai totoka. I raro i ngā āhuatanga noa, ka mau tonu te taurite hihiri o ēnei e rua hei whakarite i te rere noa o te toto i roto i ngā oko toto, ā, e kore e hanga he thrombus. Mēnā he toto toto iti, he kore inu wai, me ētahi atu, ka puhoi te rere o te toto, ka kukū te toto, ka matotoru, ka kaha rawa te mahi ārai totoka, ka ngoikore rānei te mahi ārai totoka, ka pakaru ai tēnei taurite, ka noho te tangata ki roto i te "āhua toto totoka". Ka puta te thrombosis i ngā wāhi katoa o ngā oko toto. Ka rere te thrombus me te toto i roto i ngā oko toto. Mēnā ka noho tonu ki roto i ngā uaua roro, ka aukati i te rere noa o te toto o ngā uaua roro, he thrombosis roro, ka puta he whiu ischemic. Ka taea e ngā oko coronary o te ngākau te whakaoho i te myocardial infarction, hei tāpiri atu ki te thrombosis arterial o ngā pito o raro, te thrombosis venous hohonu o ngā pito o raro, me te embolism pulmonary.

Ko te thrombosis, ko te nuinga o rātou ka pāngia e ngā tohu kino i te tīmatanga, pērā i te hemiplegia me te aphasia nā te infarction roro; te colic precordial kino i roto i te infarction myocardial; te mamae nui o te uma, te dyspnea, te hemoptysis i puta mai i te infarction pūkahukahu; Ka taea e ia te mamae i ngā waewae, te mātao rānei me te claudication wā poto. Ka taea hoki e te ngakau tino kino, te infarction roro me te infarction pūkahukahu te mate ohorere. Engari i ētahi wā kāore he tohu e kitea ana, pērā i te thrombosis uaua hohonu o te pito o raro, ko te kuao kau anake e mamae ana, e kore e pai. He maha ngā tūroro e whakaaro ana he ngenge, he mātao rānei, engari kāore rātou e aro nui ana ki tēnei, nō reira he ngawari ki te ngaro i te wā pai mō te maimoatanga. He mea tino pouri te maha o ngā tākuta e ngāwari ana ki te hē o te tātaritanga. Ina puta te pupuhi o te pito o raro, ehara i te mea ka puta he uaua ki te maimoatanga, engari ka ngawari hoki te waiho i ngā hua kino.