Mmepụta nke thrombus metụtara mmerụ ahụ nke akwara endothelial, oke mkpọchi ọbara, na mbelata ọsọ ọbara. Ya mere, ndị nwere ihe atọ a nwere ike ibute thrombus.

1. Ndị nwere mmerụ ahụ na endothelial vaskụla, dịka ndị a gbapụrụ agbapụ na vaskụla, catheterization venous, wdg, n'ihi mmebi nke vaskụla endothelium, eriri collagen ndị a na-ekpughe n'okpuru endothelium nwere ike ime ka platelets na coagulation factors rụọ ọrụ, nke nwere ike ibute coagulation endogenous. Sistemụ ahụ na-akpata thrombosis.

2. Ndị ọbara ha dị n'ọnọdụ ọbara na-anaghị agbakọ nke ọma, dịka ndị ọrịa nwere etuto ọjọọ, ọrịa lupus erythematosus nke sistemụ, mmerụ ahụ siri ike ma ọ bụ nnukwu ịwa ahụ, nwere ọtụtụ ihe na-akpata coagulation n'ọbara ha ma nwee ike ịgbakọta karịa ọbara nkịtị, yabụ ha nwere ike ibute thrombosis. Ihe atụ ọzọ bụ ndị na-aṅụ ọgwụ mgbochi afọ ime, estrogen, progesterone na ọgwụ ndị ọzọ ruo ogologo oge, ọrụ coagulation ọbara ha ga-emetụtakwa, ọ dịkwa mfe ịmepụta coagulation ọbara.

3. Ndị ọbara ha na-agba ọsọ nwayọ nwayọ, dịka ndị nọdụrụ ala ruo ogologo oge igwu egwu mahjong, ikiri TV, mụọ ihe, na-amụ ihe, ma ọ bụ nọrọ n'ihe ndina ruo ogologo oge, enweghị mmega ahụ nwere ike ime ka ọbara na-agba ọsọ nwayọ ma ọ bụ ọbụna kwụsị. Mmepụta nke vortices na-ebibi ọnọdụ ọbara nkịtị, nke ga-eme ka ohere nke platelets, mkpụrụ ndụ endothelial na ihe ndị na-akpata coagulation dịkwuo elu, ọ dịkwa mfe ịmepụta thrombus.