Ahụ mmadụ nkịtị nwere usoro coagulation zuru oke na anticoagulation. Sistemụ coagulation na sistemu anticoagulation na-ejigide nguzozi ike iji hụ na hemostasis ahụ na-aga nke ọma na ọbara na-agbagharị. Ozugbo coagulation na ọrụ anticoagulation mebiri, ọ ga-ebute ọbara ọgbụgba na thrombosis.

1. Ọrụ coagulation nke ahụ

Sistemụ coagulation bụ ihe mejupụtara ihe coagulation. A na-akpọ ihe ndị metụtara coagulation ihe coagulation. E nwere ihe coagulation iri na atọ a maara nke ọma.

E nwere ụzọ mkpali endogenous na ụzọ mkpali exogenous maka ime ka ihe coagulation rụọ ọrụ.

A kwenyere ugbu a na ime ka usoro coagulation nke sitere na ihe anụ ahụ malite na-arụ ọrụ dị mkpa na mmalite coagulation. Njikọ chiri anya dị n'etiti sistemụ coagulation dị n'ime na nke mpụga na-arụ ọrụ dị mkpa n'ịmalite na ịnọgide na-enwe usoro coagulation.

2. Ọrụ nke ọgwụ mgbochi ọbara nke ahụ

Sistemụ mgbochi coagulation gụnyere sistemu mgbochi coagulation cellular na sistemu mgbochi coagulation mmiri mmiri ahụ.

① Sistemụ mgbochi coagulation nke mkpụrụ ndụ

Na-ezo aka na phagocytosis nke ihe na-akpata coagulation, ihe na-akpata anụ ahụ, prothrombin complex na soluble fibrin monomer site na sistemụ mononuclear-phagocyte.

② Sistemụ mgbochi coagulation mmiri mmiri

Gụnyere: serine protease inhibitors, protein C-based protease inhibitors na tissue factor pathway inhibitors (TFPI).

3. Sistemụ Fibrinolytic na ọrụ ya

Karịsịa gụnyere plasminogen, plasmin, plasminogen activator na fibrinolysis inhibitor.

Ọrụ nke sistemụ fibrinolytic: gbazee mkpụkọ fibrin ma hụ na ọbara na-agbagharị nke ọma; sonye na ndozi anụ ahụ na mmeghari akwara.

4. Ọrụ nke mkpụrụ ndụ endothelial vaskụla na usoro nke coagulation, anticoagulation na fibrinolysis

① Mepụta ihe dị iche iche na-arụ ọrụ na bayoloji;

②Na-achịkwa ọrụ coagulation ọbara na igbochi coagulation;

③Hazie ọrụ nke sistemụ fibrinolysis;

④ Na-achịkwa nrụgide akwara;

⑤Soro na mgbasa ozi nke mbufụt;

⑥Debe ọrụ nke microcirculation, wdg.

Nsogbu nke coagulation na nsogbu nke usoro ọbara ọgbụgba

1. Nsogbu dị na ihe ndị na-akpata coagulation.

2. Enweghị ihe na-egbochi ihe ndị na-egbochi ọbara na plasma.

3. Enweghị ihe na-eme ka fibrinolytic factor dị na plasma.

4. Nsogbu dị iche iche nke mkpụrụ ndụ ọbara.

5. Ọkpụkpụ ọbara na-adịghị mma.