Thrombosis txheej txheem, suav nrog 2 txheej txheem:

1. Adhesion thiab aggregation ntawm platelets hauv cov ntshav

Nyob rau hauv thaum ntxov theem ntawm thrombosis, platelets yog tsis tu ncua precipitated los ntawm lub axial txaus thiab adheres rau saum npoo ntawm cov collagen fibers nyob rau hauv lub intima ntawm puas cov hlab ntsha.Platelets tau qhib los ntawm collagen thiab tso tawm cov tshuaj xws li ADP, thromboxane A2, 5-AT thiab platelet factor IV., Cov tshuaj no muaj zog ntawm agglutinating platelets, yog li cov platelets nyob rau hauv cov hlab ntsha txuas ntxiv mus rau agglutinate hauv zos los tsim ib lub pob zeb zoo li platelet pawg., pib ntawm venous thrombosis, lub taub hau ntawm thrombus.

Platelets ua raws li qhov chaw ntawm cov collagen fibers nyob rau hauv lub intima ntawm cov hlab ntsha puas thiab yog qhib kom ua ib tug hillock-zoo li platelet pawg.Lub hillock maj mam nce thiab sib tov nrog leukocytes los ua ib qho dawb thrombus.Nws muaj ntau leukocytes txuas rau nws qhov chaw.Cov ntshav ntws maj mam qeeb qeeb, lub coagulation system tau qhib, thiab ntau cov fibrin tsim cov qauv sib txuas, uas cuam tshuam ntau cov qe ntshav liab thiab cov qe ntshav dawb los ua ib qho sib xyaw thrombus.

2. Cov ntshav coagulation

Tom qab cov dawb thrombus tsim, nws protrudes mus rau hauv lub vascular lumen, ua rau cov ntshav ntws tom qab nws qeeb thiab tshwm ib tug whirlpool, thiab ib tug tshiab platelet mound yog tsim nyob rau hauv lub whirlpool.Trabeculae, zoo li coral, muaj ntau cov leukocytes txuas rau lawv qhov chaw.

Cov ntshav ntws ntawm lub trabeculae maj mam qeeb, lub coagulation system yog qhib, thiab cov concentration ntawm lub zos coagulation yam thiab platelet yam maj mam nce, ua thiab interweaving rau hauv ib tug mesh qauv ntawm lub trabeculae.Dawb thiab dawb, corrugated sib xyaw thrombus tsim lub cev ntawm thrombus.

Cov thrombus sib xyaw ua ke maj mam nce thiab txuas ntxiv mus rau cov kev taw qhia ntawm cov ntshav khiav, thiab thaum kawg tau thaiv tag nrho cov hlab ntsha lumen, ua rau cov ntshav ntws nres.