ʻO APTT ka pōkole Pelekane o ka manawa prothrombin i hoʻāla hapa ʻia. ʻO APTT kahi hoʻāʻo nānā e hōʻike ana i ke ala coagulation endogenous. Hōʻike ka APTT lōʻihi he hewa kekahi kumu coagulation koko i komo i ke ala coagulation endogenous kanaka. Ma hope o ka hoʻolōʻihi ʻia ʻana o ka APTT, e loaʻa i ka mea maʻi nā hōʻailona koko maopopo. No ka laʻana, ʻo nā mea maʻi me ka hemophilia A, hemophilia B, a me ka maʻi von Willebrand e loaʻa iā lākou ka APTT lōʻihi, a e loaʻa i ka mea maʻi ka ecchymosis ma ka ʻili a me nā membrane mucous, a me ke kahe ʻana o ke koko o nā ʻiʻo. , ke kahe ʻana o ke koko o nā hono, hematoma, a pēlā aku. ʻOi loa aku no nā mea maʻi me ka hemophilia A, waiho pinepine ʻia nā deformities hui a me ka atrophy ʻiʻo ma hope o ka komo ʻana o ka hematoma ma muli o ka synovitis i hoʻokumu ʻia e ke kahe ʻana o ke koko o nā hono, kahi hopena koʻikoʻi i ke olakino. Eia kekahi, ʻo ka coagulation intravascular disseminated, nā maʻi ate koʻikoʻi a me nā maʻi ʻē aʻe e hoʻolōʻihi nui i ka APTT, kahi e hōʻeha ai i ke kino kanaka.
ʻO ka waiwai kiʻekiʻe o Aptt e hōʻike ana e loaʻa paha i ka mea maʻi nā maʻi kahe koko. ʻO nā maʻi kahe koko maʻamau e komo pū me ka hemahema o ka coagulation factor congenital a me ka hemophilia. ʻO ka lua, ua manaʻo ʻia ua hana ʻia e ka maʻi akepaʻa a i ʻole ka jaundice obstructive a i ʻole ka maʻi thrombotic. ʻAʻole hoʻi i kāpae ʻia ua hana ʻia e ka mana o nā mea lāʻau, e like me ka hoʻohana lōʻihi ʻana i nā lāʻau anticoagulant. Ma ke ʻano lapaʻau, hiki ke hoʻohana ʻia ka hoʻāʻo aptt e hoʻoholo ai inā he maʻamau ka hana coagulation i loko o ke kino o ka mea maʻi. Inā ma muli o ka hanana i hoʻokumu ʻia e ka hemophilia, ua ʻōlelo ʻia e hahai i ka ʻōlelo aʻo a ke kauka e hoʻōki i ke kahe koko a hoʻohana paha i ka lāʻau lapaʻau prothrombin complex.