He mea hoʻoweliweli i ke ola nā maʻi coagulation, no ka mea, ʻo nā maʻi coagulation ma muli o nā kumu like ʻole e hōʻino ai i ka hana coagulation o ke kino kanaka. Ma hope o ka hana coagulation, e ʻike ʻia ke kino kanaka i kahi moʻo o nā hōʻailona koko. Inā loaʻa kahi hemorrhage intracranial koʻikoʻi, he mea hoʻoweliweli loa ia i ke ola. No ka mea, hiki ke hana ʻia ka hana coagulation e nā ʻano maʻi like ʻole, ʻoi aku ka maʻamau o ka nele o ka vitamin K, ka coagulation intravascular disseminated, ka maʻi ate koʻikoʻi, ka hemophilia a, ka hemophilia b, ka maʻi von Willebrand, a pēlā aku. Hiki ke loaʻa nā maʻi coagulation i kēia mau maʻi.

Inā he maʻi me ka hemophilia A koʻikoʻi, he ʻano maopopo kona e kahe ke koko, a he maʻalahi ke hoʻoulu i ke kahe koko ma hope o kahi trauma iki. Inā loaʻa i kahi maʻi me ka hemophilia A koʻikoʻi ka trauma, he maʻalahi ke hoʻoulu i ke kahe koko nui o ka lolo, kahi e hoʻoweliweli ai i ke ola o ka mea maʻi. Eia kekahi, ʻo ka coagulation intravascular disseminated koʻikoʻi he mea maʻalahi hoʻi i ke kahe koko nui ma muli o ka ʻai ʻana i nā mea coagulation like ʻole a me ka hana coagulation, e alakaʻi ana i ka make mua o nā mea maʻi.