Loaʻa i ke kino maʻamau kahi ʻōnaehana coagulation a me anticoagulation piha. Mālama ka ʻōnaehana coagulation a me ka ʻōnaehana anticoagulation i kahi kaulike ikaika e hōʻoia i ka hemostasis o ke kino a me ke kahe koko maʻalahi. Ke hoʻopilikia ʻia ke kaulike o ka hana coagulation a me ka anticoagulation, e alakaʻi ia i ke kahe koko a me ke ʻano thrombosis.

1. Ka hana coagulation o ke kino

ʻO ka ʻōnaehana coagulation ka mea nui i haku ʻia me nā mea coagulation. ʻO nā mea e pili pono ana i ka coagulation ua kapa ʻia he mau mea coagulation. Aia he 13 mau mea coagulation i ʻike ʻia.

Aia nā ala hoʻāla endogenous a me nā ala hoʻāla exogenous no ka hoʻāla ʻana o nā mea coagulation.

I kēia manawa, ua manaʻoʻiʻo ʻia ʻo ka hoʻoulu ʻana o ka ʻōnaehana coagulation exogenous i hoʻomaka ʻia e ka tissue factor e pāʻani i kahi kuleana nui i ka hoʻomaka ʻana o ke coagulation. ʻO ka pilina pili ma waena o nā ʻōnaehana coagulation kūloko a me waho e pāʻani i kahi kuleana koʻikoʻi i ka hoʻomaka ʻana a me ka mālama ʻana i ke kaʻina hana coagulation.

2. Ka hana anticoagulant o ke kino

ʻO ka ʻōnaehana anticoagulation e komo pū me ka ʻōnaehana anticoagulation cellular a me ka ʻōnaehana anticoagulation wai o ke kino.

①ʻŌnaehana anticoagulation cell

Pili ia i ka phagocytosis o ka coagulation factor, tissue factor, prothrombin complex a me ka soluble fibrin monomer e ka ʻōnaehana mononuclear-phagocyte.

②ʻŌnaehana anticoagulation wai kino

ʻO ia hoʻi: nā mea hoʻopaʻa serine protease, nā mea hoʻopaʻa protease e pili ana i ka protein C a me nā mea hoʻopaʻa alahele tissue factor (TFPI).

3. ʻŌnaehana Fibrinolytic a me kāna mau hana

ʻO ka mea nui e komo pū me ka plasminogen, plasmin, plasminogen activator a me ka fibrinolysis inhibitor.

ʻO ke kuleana o ka ʻōnaehana fibrinolytic: hoʻoheheʻe i nā ʻōpū fibrin a hōʻoia i ke kahe koko maʻemaʻe; komo i ka hoʻoponopono ʻana i nā ʻiʻo a me ka hana hou ʻana o nā kīʻaha koko.

4. Ke kuleana o nā pūnaewele endothelial vascular i ke kaʻina hana o ka coagulation, anticoagulation a me ka fibrinolysis

① Hana i nā mea olaola like ʻole;

②Hoʻoponopono i ke kāpili ʻana o ke koko a me ka hana anticoagulation;

③E hoʻoponopono i ka hana o ka ʻōnaehana fibrinolysis;

④ Hoʻoponopono i ke koʻikoʻi o nā kīʻaha koko;

⑤E komo i ka hoʻoponopono ʻana i ka mumū;

⑥E mālama i ka hana o ka microcirculation, etc.

Nā maʻi coagulation a me nā anticoagulant

1. Nā ʻano ʻē i nā kumu coagulation.

2. ʻAno ʻē o nā mea anticoagulant i loko o ka plasma.

3. ʻAno ʻē o ka fibrinolytic factor i loko o ka plasma.

4. Nā ʻano ʻē o nā hunaola koko.

5. Nā kīʻaha koko ʻē.