Pahu Manawa Thromboplastin hapa i hoʻāla ʻia (APTT)

ʻO ke ana ʻana o APTT ka hoʻāʻo nānā ʻike lapaʻau i hoʻohana pinepine ʻia e hōʻike i ka hana coagulation o ka ʻōnaehana coagulation endogenous. Hoʻohana ʻia ia e ʻike i nā hemahema o ka coagulation factor endogenous a me nā mea hoʻopaʻa pili a e nānā i ka hanana o ke kū'ē ʻana o ka protein C i hoʻāla ʻia. Loaʻa iā ia kahi ākea o nā noi e pili ana i ka nānā ʻana, ka nānā ʻana i ka lāʻau heparin, ka ʻike mua ʻana o ka disseminated intravascular coagulation (DIC), a me ka hoʻokolokolo mua ʻana.

Ke koʻikoʻi lapaʻau:

ʻO APTT kahi helu hoʻāʻo hana coagulation e hōʻike ana i ke ala coagulation endogenous, ʻoi aku ka hana piha o nā mea coagulation i ke kahua mua. Hoʻohana nui ʻia ia e nānā a hoʻoholo i nā hemahema o nā mea coagulation i ke ala endogenous, e like me ka mea Ⅺ, Ⅷ, Ⅸ, hiki ke hoʻohana ʻia no ka ʻike mua ʻana i nā maʻi kahe koko a me ka nānā ʻana i ka hale hana o ka lāʻau heparin anticoagulation.

1. Lōʻihi: hiki ke ʻike ʻia ma ka hemophilia A, hemophilia B, maʻi ake, intestinal sterilization syndrome, oral anticoagulants, diffuse intravascular coagulation, mild hemophilia; FXI, FXII deficiency; ua hoʻonui ʻia nā mea Anticoagulant koko (coagulation factor inhibitors, lupus anticoagulants, warfarin a heparin paha); ua hoʻoili ʻia ka nui o ke koko i mālama ʻia.

2. Hoʻopōkole: Hiki ke ʻike ʻia i ke kūlana hypercoagulable, nā maʻi thromboembolic, a pēlā aku.

Pae kuhikuhi o ka waiwai maʻamau

ʻO ka waiwai kuhikuhi maʻamau o ka manawa thromboplastin hapa i hoʻāla ʻia (APTT): 27-45 kekona.

Nā Mālama

1. E pale i ka hemolysis o ka hāpana. Loaʻa i ka hāpana hemolyzed nā phospholipids i hoʻokuʻu ʻia e ka haki ʻana o ka membrane cell koko ʻulaʻula makua, ka mea e hoʻohaʻahaʻa ai i ka APTT ma mua o ka waiwai i ana ʻia o ka hāpana i hemolyzed ʻole.

2. ʻAʻole pono nā mea maʻi e hana i nā hana ikaika i loko o 30 mau minuke ma mua o ka loaʻa ʻana o ke koko.

3. Ma hope o ka hōʻiliʻili ʻana i ka hāpana koko, e lūlū mālie i ka ʻōmole hoʻāʻo me ka hāpana koko 3 a 5 mau manawa i mea e hoʻohui piha ai i ka hāpana koko me ka anticoagulant i loko o ka ʻōmole hoʻāʻo.

4. Pono e hoʻouna ʻia nā hāpana koko no ka hoʻokolokolo ʻana i ka hikiwawe loa.