1. Ngokuqapha umkhuba oshintshayo we-AT, ukusebenza kwe-placenta yayo, ukukhula kwengane, kanye nokuqaphela ukwenzeka kwe-eclamps kusenesikhathi kungahlolwa.

2. Omama abakhulelwe abane-heparin yama-molecule aphansi noma i-heparin evamile yokulwa nokujiya kwegazi bangasetshenziswa ukuhlola ukusebenza kahle kwe-heparin anticoagulation ngomsebenzi we-AT ukuvikela imiphumela elindelekile ye-anticoagulant ye-heparin.

3. Ukukhipha isisu okuphindaphindiwe ngesikhathi sokukhulelwa, amathayi afile noma imithi yokuvimbela inzalo, kanye ne-thrombosis ebambekile ngemuva kwe-hormone kungatholakala ukuthola izimbangela ze-thromellar kalula ngokutholwa kwe-AT, PC, PS kanye ne-APL.