Ukopha okungaphansi kwesikhumba kudinga ukuhlolwa okulandelayo:
1. Ukuhlolwa komzimba
Ukusabalala kokuphuma kwegazi ngaphansi kwesikhumba, ukuthi ububanzi be-ecchymosis purpura kanye ne-ecchymosis buphakeme kunobuso besikhumba, ukuthi siyaphela yini, ukuthi sihambisana nokulunywa nobuhlungu, ukuthi kukhona ukopha kwezinsini, ukopha ekhaleni, umkhuhlane, nokuthi ngabe kukhona yini izimpawu ze-anemia njengesikhumba esimpunga, umbhede wezinzipho, kanye ne-sclera.
2. Ukuhlolwa kwelebhu
Kubandakanya inani lama-platelet, inani legazi, inani lomnkantsha, umsebenzi wokuqina kwamathambo, umsebenzi wesibindi nezinso, ukuhlolwa kwe-immunological, i-D-dimer, inqubo yomchamo, inqubo yendle, njll.
3. Ukuhlolwa kwezithombe
Ukuhlolwa kwe-X-ray, i-CT, i-magnetic resonance imaging (MRI), noma ukuhlolwa kwe-PET/CT kwezilonda zamathambo kungasiza ekuxilongweni kweziguli ze-myeloma ezinezinhlungu zamathambo.
4. Ukuhlolwa kwezifo
Ukuhlolwa okuqondile kwe-immunofluorescence kwezilonda zesikhumba kanye nesikhumba esizungezile kuveza ukwakheka kwe-IgA, i-complement, kanye ne-fibrin, okungasetshenziswa ukuxilonga i-allergy purpura, njll.
5. Ukuhlolwa okukhethekile
Ukuhlolwa kobuthakathaka be-capillary kungasiza ekuxilongeni imbangela yokopha kwegazi ngaphansi kwesikhumba ngokuhlola ukuthi kukhona yini ukwanda kobuthakathaka bemithambo yegazi noma umonakalo ku-intima yemithambo yegazi, kanye nokuthi kukhona yini ukungalingani ngobuningi noma ikhwalithi yama-platelet.