Umehluko omkhulu phakathi kokuhlanganiswa kwegazi kanye nokujiya kwegazi ukuthi ukuhlanganiswa kwegazi kubhekisela ekuhlanganisweni kwamaseli abomvu egazi nama-platelet egazini abe amabhlogo ngaphansi kokukhuthazwa kwangaphandle, kuyilapho ukuhlangana kwegazi kubhekisela ekwakhekeni kwenethiwekhi yokujiya ngokusebenzisa izinto ezijiya egazini ngokusebenzisa uchungechunge lwezimpendulo ze-enzyme.

1. Ukuhlanganiswa kwegazi kuyinqubo esheshayo neguqukayo eyakhiwa kakhulu ukuhlanganiswa kwamaseli abomvu egazi nama-platelet, ngokuvamile okwenzeka ngaphansi kwezinto ezibangela ukulimala noma ukuvuvukala. Ukuhlanganiswa kwegazi kuyinqubo ehamba kancane futhi engenakuguqulwa eyakha kakhulu inethiwekhi yokwakheka kwegazi ngokusebenzisa uchungechunge lwezimpendulo eziyinkimbinkimbi ezibangelwa yi-thrombin, ngokuvamile ezenzeka ngesikhathi sokulimala kwemithambo yegazi.

2. Inhloso eyinhloko yokuhlanganiswa kwegazi ukwakha amahlule egazi ukuvimbela ukuphuma kwegazi. Inhloso eyinhloko yokuhlanganiswa kwegazi ukwakha amahlule egazi endaweni yokulimala kwemithambo yegazi, ukulungisa imithambo yegazi, nokuyeka ukuphuma kwegazi.

3. Ukujiya kwegazi kuhilela kakhulu ukuhlanganiswa kwamaseli abomvu egazi nama-platelet, kuyilapho ukujiya kwegazi kuhilela kakhulu ukusebenza nokuhlanganiswa kwezinto ezijiyayo, ama-enzyme, kanye ne-fibrinogen ku-plasma.

4. Ngesikhathi senqubo yokuhlangana kwegazi, i-thrombus eyakheka ngokuhlangana kwamangqamuzana abomvu egazi nama-platelet ikhululekile futhi ithambekele ekuqhekekeni. Ngesikhathi senqubo yokuhlangana kwegazi, ama-fibrin clots akhiwe azinzile futhi kunzima ukuwaqhekeka.

5. Ukujiya kwegazi kuvame ukwenzeka endaweni lapho kwenzeke khona ingozi noma ukuvuvukala, kuyilapho ukujiya kwegazi kuvame ukwenzeka ngaphakathi kwemithambo yegazi, ikakhulukazi ezindongeni zemithambo yegazi ezonakele.

Kufanele kuqashelwe ukuthi ukuhlangana kwegazi kanye nokujiya kwegazi kuyizinqubo ezimbili ezihlobene kodwa ezihlukene zomzimba. Ukuphazamiseka kokujiya kwegazi kanye nokujiya kwegazi kungaholela ezifweni ezifana nokopha noma i-thrombosis, ngakho-ke ukufunda izindlela zalo kubaluleke kakhulu emtholampilo.