I-PT isho isikhathi se-prothrombin kwezokwelapha, kanti i-APTT isho isikhathi se-thromboplastin esingasebenzi kahle kwezokwelapha. Umsebenzi wokuqina kwegazi emzimbeni womuntu ubaluleke kakhulu. Uma umsebenzi wokuqina kwegazi ungajwayelekile, kungaholela ekuqhekekeni kwegazi noma ekuphumeni kwegazi, okungabeka impilo yesiguli engozini enkulu. Ukuqapha ngokwezokwelapha amanani e-PT kanye ne-APTT kungasetshenziswa njengendinganiso yokusebenzisa eminye imithi yokuvimbela ukuminyana kwegazi emtholampilo. Uma amanani alinganisiwe ephezulu kakhulu, kusho ukuthi umthamo wemithi yokuvimbela ukuminyana kwegazi udinga ukuncishiswa, ngaphandle kwalokho ukopha kuzokwenzeka kalula.

1. Isikhathi se-Prothrombin (PT): Kungenye yezinkomba ezibucayi kakhulu zesistimu yokujiya kwegazi lomuntu. Kubaluleke kakhulu ukwelula isikhathi isikhathi esingaphezu kwemizuzwana emi-3 emtholampilo, okungabonisa ukuthi umsebenzi wokujiya kwegazi wangaphandle ujwayelekile yini. Ukujiya kwegazi ngokuvamile kubonakala ekujiya kwegazi kokuzalwa Ukuntuleka kwe-Factor, i-cirrhosis enzima, ukwehluleka kwesibindi nezinye izifo. Ngaphezu kwalokho, imithamo eminingi ye-heparin ne-warfarin ingabangela ne-PT ende;

2. Isikhathi se-thromboplastin esingaphelele esisebenzayo (i-APTT): Ngokuyinhloko siyinkomba ebonisa umsebenzi wokujiya kwegazi emvelweni emtholampilo. Ukwelulwa okukhulu kwe-APTT kubonakala kakhulu ekushodeni kwe-congenital noma okutholiwe kwe-coagulation factor, njenge-hemophilia kanye ne-systemic lupus erythematosus. Uma umthamo wemithi yokulwa nokujiya kwegazi esetshenziswa ngenxa ye-thrombosis ungavamile, uzophinde ubangele ukwelulwa okukhulu kwe-APTT. Uma inani elilinganisiwe liphansi, cabanga ukuthi isiguli sisesimweni sokujiya kwegazi, njenge-deep vein thrombosis.

Uma ufuna ukwazi ukuthi i-PT yakho kanye ne-APTT yakho zijwayelekile yini, udinga ukucacisa ububanzi bazo obujwayelekile. Ububanzi obujwayelekile be-PT buyimizuzwana eyi-11-14, kanti ububanzi obujwayelekile be-APTT buyimizuzwana engama-27-45. Ukwelulwa kwe-PT okungaphezu kwemizuzwana emi-3 kunokubaluleka okukhulu kwezokwelapha, kanti ukwelulwa kwe-APTT okungaphezu kwemizuzwana eyi-10 kunokubaluleka okukhulu kwezokwelapha.