Kunezinhlelo zokubopha igazi kanye nezinhlelo zokuvimbela ukujiya kwegazi egazini lomuntu. Ngaphansi kwezimo ezijwayelekile, lezi ezimbili zigcina ibhalansi enamandla ukuqinisekisa ukugeleza kwegazi okuvamile emithanjeni yegazi, futhi ngeke zakhe i-thrombus. Uma umfutho wegazi uphansi, ukuntuleka kwamanzi okuphuza, njll., ukugeleza kwegazi kuzoba kancane, igazi lizogxila futhi liqine, umsebenzi wokubopha igazi uzoba namandla kakhulu noma umsebenzi wokuvimbela ukujiya kwegazi uzoba buthaka, okuzophula leli bhalansi futhi kwenze abantu babe "sesimweni se-thrombotic". I-Thrombosis ingenzeka noma kuphi emithanjeni yegazi. I-thrombus igeleza negazi emithanjeni yegazi. Uma ihlala emithanjeni yobuchopho futhi ivimbele ukugeleza kwegazi okuvamile emithanjeni yobuchopho, kuyi-thrombosis yobuchopho, okuzobangela i-ischemic stroke. Imithambo yenhliziyo yenhliziyo ingabangela i-myocardial infarction, ngaphezu kwalokho, i-arterial thrombosis ephansi, i-venous thrombosis ejulile emithanjeni ephansi, kanye ne-pulmonary embolism.

I-Thrombosis, iningi labo lizoba nezimpawu ezinkulu ekuqaleni, njenge-hemiplegia kanye ne-aphasia ngenxa ye-cerebral infarction; i-precordial colic enzima kakhulu ku-myocardial infarction; ubuhlungu obukhulu besifuba, ukuphelelwa umoya, i-hemoptysis ebangelwa yi-pulmonary infarction; Kungabangela ubuhlungu emilenzeni, noma umuzwa wokubanda kanye ne-claudication ngezikhathi ezithile. Inhliziyo embi kakhulu, i-cerebral infarction kanye ne-pulmonary infarction nakho kungabangela ukufa okuzumayo. Kodwa ngezinye izikhathi azikho izimpawu ezisobala, njenge-common deep vein thrombosis yengxenye engezansi, kuphela ithole elibuhlungu futhi elingakhululekile. Iziguli eziningi zicabanga ukuthi kungenxa yokukhathala noma umkhuhlane, kodwa azikuthathi ngokungathi sína, ngakho-ke kulula ukuphuthelwa isikhathi esingcono kakhulu sokwelashwa. Kuyadabukisa kakhulu ukuthi odokotela abaningi bathambekele ekuxilongweni okungalungile. Lapho kwenzeka ukuvuvukala kwengxenye engezansi, ngeke nje kulethe ubunzima ekwelashweni, kodwa futhi kuzoshiya kalula imiphumela.