Izinto ezibangela ukujiya kwegazi kanye ne-thrombin akuzona izidakamizwa ezifanayo. Ziyahlukahluka ngokwakheka, indlela yokusebenza kanye nobubanzi bokusetshenziswa, kanje:

Ukwakheka kanye nezakhiwo
Izici zokubopha: izingxenye ezahlukahlukene zamaprotheni ezihilelekile enqubweni yokubopha igazi, okuhlanganisa izici zokubopha igazi Ⅰ (i-fibrinogen), Ⅱ (i-prothrombin), Ⅴ, Ⅶ, Ⅷ, Ⅸ, Ⅹ, Ⅺ, Ⅻ nezinye izici. Iningi lazo ngamaprotheni enziwe esibindini futhi akhona egazini njengezinto ezibangela ukungasebenzi.
I-Thrombin: i-serine protease eyakhiwa ukusebenza kwe-prothrombin kanye ne-enzyme ebalulekile ku-coagulation cascade.

Indlela yokwenza
Izici zokubopha: zisebenza ngochungechunge lwezindlela zokusabela eziyinkimbinkimbi ze-enzyme, ekugcineni ziguqula i-fibrinogen ibe yi-fibrin ukuze kwakheke ihlule legazi. Izici zokubopha ezahlukene zidlala indima ehlukene kule nqubo, isibonelo, izici zokubopha Ⅷ kanye Ⅸ zihlanganyela endleleni yokubopha yangaphakathi, kanti i-coagulation factor Ⅶ ihlanganyela endleleni yokubopha yangaphandle, njll.
I-Thrombin: isebenza ngqo ku-fibrinogen, iyisika ibe ama-monomers e-fibrin, abese ehlangana ukuze akhe inethiwekhi ye-fibrin ezinzile, okubangela ukuba igazi lijiye. Ngesikhathi esifanayo, i-thrombin ingaphinde isebenze ama-platelet, ikhuthaze ukuhlanganiswa kwama-platelet, futhi iqinise inqubo yokuqina kwama-platelet.

Ububanzi besicelo
Izici zokubopha: ezisetshenziswa kakhulu ukwelapha izifo zokopha ezibangelwa ukuntuleka kwe-coagulation factor, njenge-hemophilia A (ukuntuleka kwe-coagulation factor VIII), i-hemophilia B (ukuntuleka kwe-coagulation factor IX), kanye nokuntuleka kwe-coagulation factor II, VII, IX, kanye ne-X okubangelwa ukuntuleka kwe-vitamin K.
I-Thrombin: ivame ukusetshenziswa ekunqandeni kwegazi endaweni, njengokuphuma kwegazi emanxebeni okuhlinzwa kanye namanxeba abuhlungu, futhi ingasetshenziswa nasekuphumeni kwegazi emathunjini, njengokumiliswa ngomlomo noma endaweni ukuze kwelashwe ukuphuma kwegazi emanxebeni esiswini nase-duodenal.
Izinto ezibangela ukujiya kwegazi kanye ne-thrombin zombili zidlala indima ebalulekile enqubweni yokujiya kwegazi, kodwa ziyizinto ezihlukile futhi ukusetshenziswa kwazo kwezokwelapha nakho kuhlukile.

I-Beijing Succeeder Technology Inc. (Ikhodi yesitoko: 688338), eyasungulwa ngo-2003 futhi yafakwa ohlwini kusukela ngo-2020, ingumkhiqizi ohamba phambili ekuxilongweni kwe-coagulation. Singochwepheshe ekuhlaziyeni kwe-coagulation okuzenzakalelayo kanye nama-reagent, abahlaziyi be-ESR/HCT, kanye nabahlaziyi be-hemorheology. Imikhiqizo yethu iqinisekiswe ngaphansi kwe-ISO 13485 kanye ne-CE, futhi siphakela abasebenzisi abangaphezu kwe-10,000 emhlabeni jikelele.

Isingeniso Sokuhlaziya
Isihlaziyi se-Coagulation Esizenzakalelayo Ngokugcwele i-SF-9200 (https://www.succeeder.com/fully-automated-coagulation-analyzer-sf-9200-product) singasetshenziswa ekuhlolweni kwezokwelapha kanye nokuhlolwa kwangaphambi kokuhlinzwa. Izibhedlela kanye nabacwaningi besayensi yezokwelapha nabo bangasebenzisa i-SF-9200. Esebenzisa i-coagulation kanye ne-immunoturbidimetry, indlela ye-chromogenic yokuhlola i-clotting ye-plasma. Ithuluzi libonisa ukuthi inani lokulinganisa i-clotting yisikhathi sokujiya (ngemizuzwana). Uma into yokuhlola ilinganiswa yi-plasma yokulinganisa, ingabonisa neminye imiphumela ehlobene.
Lo mkhiqizo wenziwe ngeyunithi enyakazayo ye-probe yokubonisa isampula, iyunithi yokuhlanza, iyunithi enyakazayo yama-cuvettes, iyunithi yokushisa nokupholisa, iyunithi yokuhlola, iyunithi eboniswa ukusebenza, isikhombimsebenzisi se-LIS (esetshenziselwa iphrinta nosuku lokudlulisela kwiKhompyutha).
Abasebenzi bezobuchwepheshe nabanolwazi kanye nabahlaziyi bekhwalithi ephezulu kanye nokuphathwa kwekhwalithi okuqinile bayisiqinisekiso sokukhiqizwa kwe-SF-9200 kanye nekhwalithi enhle. Siqinisekisa ukuthi ithuluzi ngalinye lihlolwe futhi lihlolwe ngokuqinile. I-SF-9200 ihlangabezana nezindinganiso zikazwelonke zaseShayina, amazinga emboni, amazinga ebhizinisi kanye nezindinganiso ze-IEC.