Ukuqonda umthamo wokujiya kwegazi: uluhlu oluqhelekileyo kunye nokubaluleka kwempilo

Kwicandelo lezempilo yezonyango, umsebenzi wokujiya kwegazi likhonkco eliphambili ekugcineni imeko eqhelekileyo yomzimba womntu. Umthamo wokujiya kwegazi, odla ngokulinganiswa zizalathisi ezinxulumene nokujiya kwegazi, udlala indima ebalulekileyo ekugwebeni imeko yempilo yomzimba womntu. Ngoko ke, lingakanani inani eliqhelekileyo lokujiya kwegazi? Le ngxaki inxulumene nokuxilongwa kunye nonyango lwezigulane ezininzi, kwaye ikwatsale ingqalelo enkulu kwiingcali zonyango nakuluntu.

Ngokubanzi, izalathi zovavanyo lomsebenzi wokuxinana kwemithambo ezisetyenziswa rhoqo kwiklinikhi ziquka ixesha le-prothrombin (PT), ixesha le-activated partial thromboplastin (APTT), ixesha le-thrombin (TT) kunye ne-fibrinogen (FIB).
Uluhlu oluqhelekileyo lwezi mpawu zezi:
Ixesha le-Prothrombin (PT) lidla ngokuba phakathi kwemizuzwana eli-10 neli-14, kwaye libalulekile ngokwezonyango ukuba lidlula ulawulo oluqhelekileyo ngemizuzwana engaphezu kwemi-3;
Ixesha eliqhelekileyo le-activated partial thromboplastin time (APTT) liphakathi kwemizuzwana engama-25 ukuya kwengama-37, kwaye ukuba lidlula ixesha eliqhelekileyo lokulawula ngaphezu kwemizuzwana eli-10, kufuneka lithathwe nzulu;
Ixesha eliqhelekileyo le-thrombin (TT) liyimizuzwana eli-12 ukuya kweli-16, kwaye ukudlula ulawulo oluqhelekileyo ngemizuzwana engaphezu kwemi-3 kubonisa ukuba kusenokubakho izinto ezingaqhelekanga;
Umthamo oqhelekileyo we-fibrinogen (FIB) uphakathi kwe-2 kunye ne-4g/L.

Nangona kunjalo, kufuneka kuqatshelwe ukuba ngenxa yokwahluka kwiindlela zokuhlola, ii-reagents kunye nezixhobo ezisetyenziswa zizibhedlele ezahlukeneyo, uluhlu oluqhelekileyo lwamaxabiso okujiya lunokwahluka kancinci. Ke ngoko, uluhlu oluthile oluqhelekileyo lwereferensi kufuneka lusekelwe kwifomu yengxelo yesibhedlele apho isigulane sinyangwa khona.

Umthamo ongaqhelekanga wokujiya kwegazi udla ngokunxulunyaniswa kakhulu nezifo ezahlukeneyo. Xa umthamo wokujiya kwegazi uphezulu kakhulu, kusenokwenzeka ukuba kungenxa yezifo ezifana ne-thrombocytosis, i-polycythemia vera, kunye ne-dispersed intravascular coagulation, ezonyusa ukujiya kwegazi kwaye ngaloo ndlela zonyusa umngcipheko we-thrombosis. Ukongeza, amanye amayeza afana ne-anticoagulants (i-heparin, i-warfarin), amayeza e-antiplatelet (i-aspirin, i-clopidogrel), amayeza e-chemotherapy, kunye nonyango olufana ne-hemodialysis kunye ne-extracorporeal membrane oxygenation (ECMO) nazo zinokuchaphazela umsebenzi wokujiya kwegazi, nto leyo ebangela ukujiya kwegazi okugqithisileyo. Ngokwahlukileyo koko, umsebenzi wokujiya kwegazi okungaqhelekanga unokubangelwa kukunqongophala kwezinto zokujiya kwegazi, ukunqongophala kwe-vitamin K, i-thrombocytopenia, ukusetyenziswa kakhulu kwe-anticoagulants, kunye nezifo zokusebenzisa izinto zokujiya kwegazi. Ezi meko zinokukhokelela kwiingxaki zokujiya kwegazi kwaye zinokopha.

Kuluntu, kubaluleke kakhulu ukuqonda uluhlu oluqhelekileyo lomthamo wokujiya kwegazi kunye nolwazi olufanelekileyo ngomsebenzi wokujiya kwegazi ongaqhelekanga. Ukuba umthamo wokujiya kwegazi ongaqhelekanga ufunyenwe ngexesha lovavanyo lomzimba okanye unyango, kufuneka ugqirha adibane naye ngexesha ukuze acacise unobangela kwaye athathe amanyathelo afanelekileyo onyango. Kwangaxeshanye, ukuvavanywa rhoqo komzimba kunye nokugcina indlela yokuphila esempilweni nako kulungile ekugcineni umsebenzi wokujiya kwegazi oqhelekileyo.

I-Beijing Succeeder Technology Inc. (ikhowudi yesitokhwe: 688338) ibisoloko ibandakanyeka kakhulu kwicandelo lokuxilongwa kwe-coagulation ukususela ekusekweni kwayo ngo-2003, kwaye izimisele ukuba yinkokeli kweli candelo. Ikomkhulu layo liseBeijing, le nkampani ineqela elinamandla le-R&D, lemveliso kunye nelokuthengisa, eligxile ekuveliseni izinto ezintsha kunye nokusetyenziswa kwetekhnoloji yokuxilonga i-thrombosis kunye ne-hemostasis.

Ngenxa yamandla ayo abalaseleyo obuchwephesha, iSucceeder iphumelele iipatenti ezingama-45 ezigunyazisiweyo, kuquka iipatenti zokuyila ezili-14, iipatenti zemodeli yokusetyenziswa ezili-16 kunye neepatenti zoyilo ezili-15. Le nkampani ikwanazo nezatifikethi zobhaliso lwemveliso yezixhobo zonyango zeKlasi yesiBini ezingama-32, izatifikethi zokufaka iifayile zeKlasi yoku-1 ezi-3, kunye nesatifikethi se-EU CE kwiimveliso ezili-14, kwaye iphumelele isatifikethi senkqubo yolawulo lomgangatho se-ISO 13485 ukuqinisekisa ukugqwesa kunye nokuzinza komgangatho wemveliso.

I-Succeeder ayisiyo nje kuphela ishishini eliphambili leBeijing Biomedicine Industry Leapfrog Development Project (G20), kodwa ikwaphumelele kwiBhodi yoBuchule beSayensi neTekhnoloji ngo-2020, ifezekisa uphuhliso oluphezulu lwenkampani. Okwangoku, inkampani yakhe inethiwekhi yokuthengisa kuzwelonke egubungela amakhulu eearhente kunye neeofisi. Iimveliso zayo zithengiswa kakuhle kwiindawo ezininzi zelizwe. Ikwakhulisa ngokukhutheleyo iimarike zaphesheya kwaye iphucula rhoqo ukhuphiswano lwayo lwamazwe ngamazwe.