Umahluko ophambili phakathi kokuhlanganiswa kwegazi kunye nokuxinana kwegazi kukuba ukuhlanganiswa kwegazi kubhekisa ekuhlanganisweni kweeseli ezibomvu zegazi kunye neeplatelets egazini zibe ziibhloko phantsi kokukhuthazwa kwangaphandle, ngelixa ukuhlanganiswa kwegazi kubhekisa ekwakhiweni kwenethiwekhi yokuxinana kwegazi ngezinto ezixinana egazini ngokusebenzisa uthotho lwee-enzyme reactions.

1. Ukuhlanganiswa kwegazi yinkqubo ekhawulezayo neguqukayo eyenziwa ngokuhlanganisana kweeseli ezibomvu zegazi kunye neeplatelets, ngokuqhelekileyo eyenzeka phantsi kwezinto ezifana nokwenzakala okanye ukudumba. Ukuhlanganiswa kwegazi yinkqubo ecothayo nengaguqukiyo eyenza ngokuyintloko inethiwekhi yokudibanisa igazi ngothotho lweempendulo ezintsonkothileyo ze-thrombin, ngokuqhelekileyo ezenzeka ngexesha lokwenzakala kwemithambo yegazi.

2. Eyona njongo iphambili yokuhlanganiswa kwegazi kukwenza amahlwili egazi ukuthintela ukopha. Eyona njongo iphambili yokuhlanganiswa kwegazi kukwenza amahlwili egazi kwindawo yokwenzakala kwemithambo yegazi, ukulungisa imithambo yegazi, kunye nokuyeka ukopha.

3. Ukujiya kwegazi kubandakanya ikakhulu ukuhlanganiswa kweeseli ezibomvu zegazi kunye neeplatelets, ngelixa ukujiya kwegazi kubandakanya kakhulu ukusebenza kunye nokuhlanganiswa kwezinto ezijiyayo, ii-enzymes, kunye ne-fibrinogen kwi-plasma.

4. Ngexesha lenkqubo yokuhlanganiswa kwegazi, i-thrombus eyenziwe kukuhlanganiswa kweeseli ezibomvu zegazi kunye neeplatelets ikhululekile kwaye ithambekele ekuqhekekeni. Ngexesha lenkqubo yokuqina kwegazi, amahlwili e-fibrin enziweyo azinzile kwaye kunzima ukuwaqhekeka.

5. Ukujiya kwegazi kudla ngokuvela kwindawo apho kwenzeke khona ingozi okanye ukudumba, ngelixa ukujiya kwegazi kudla ngokuvela ngaphakathi kwemithambo yegazi, ingakumbi kwiindonga zemithambo yegazi ezonakeleyo.

Kufuneka kuqatshelwe ukuba ukuhlangana kwegazi kunye nokujiya kwegazi ziinkqubo ezimbini ezinxulumeneyo kodwa ezahlukeneyo zefiziyoloji. Ukuphazamiseka kokujiya kwegazi kunye nokujiya kwegazi kunokukhokelela kwizifo ezifana nokopha okanye i-thrombosis, ngoko ke ukufunda iindlela zayo kubaluleke kakhulu kwezonyango.