I-PT ithetha ixesha le-prothrombin kunyango, kwaye i-APTT ithetha ixesha le-thromboplastin elingasebenziyo kwicandelo lezonyango. Umsebenzi wokuqina kwegazi emzimbeni womntu ubaluleke kakhulu. Ukuba umsebenzi wokuqina kwegazi awuqhelekanga, unokukhokelela kwi-thrombosis okanye ukopha, okunokubeka ubomi besigulana emngciphekweni omkhulu. Ukubekwa esweni kweklinikhi kwamaxabiso e-PT kunye ne-APTT kunokusetyenziswa njengomgangatho wokusetyenziswa kwamanye amayeza okunqanda ukopha kwegazi kunyango. Ukuba amaxabiso alinganisiweyo aphezulu kakhulu, kuthetha ukuba umthamo wamayeza okuthintela ukopha kufuneka uncitshiswe, kungenjalo ukopha kuya kwenzeka ngokulula.

1. Ixesha leProthrombin (PT): Lelinye lawona mabonakaliso abuthathaka kakhulu enkqubo yokujiya kwegazi lomntu. Kubaluleke ngakumbi ukwandisa ixesha elingaphezulu kwemizuzwana emi-3 kunyango lweklinikhi, nto leyo enokubonisa ukuba umsebenzi wokujiya kwegazi ngaphandle uqhelekile na. Ukwandiswa kwexesha kubonakala ngokubanzi kwi-congenital coagulation deficiency Factor, i-cirrhosis enzima, ukusilela kwesibindi kunye nezinye izifo. Ukongeza, iidosi ezininzi ze-heparin kunye ne-warfarin zinokubangela i-PT ende;

2. Ixesha le-thromboplastin elingasebenziyo (i-APTT): Ngokuyintloko libonisa umsebenzi wokujiya kwegazi okwenziwa emizimbeni kwiklinikhi. Ukwandiswa okuphawulekayo kwe-APTT kubonakala kakhulu kwi-congenital okanye i-acquired coagulation factor deficiency, efana ne-hemophilia kunye ne-systemic lupus erythematosus. Ukuba umthamo wamayeza okujiya igazi asetyenziswa ngenxa ye-thrombosis awuqhelekanga, uya kubangela nokwandiswa okuphawulekayo kwe-APTT. Ukuba ixabiso elilinganisiweyo liphantsi, cinga ukuba isigulana sikwimeko yokujiya kwegazi okugqithisileyo, njenge-deep vein thrombosis.

Ukuba ufuna ukwazi ukuba i-PT kunye ne-APTT yakho ziqhelekile na, kufuneka ucacise uluhlu lwazo oluqhelekileyo. Uluhlu oluqhelekileyo lwe-PT yimizuzwana eli-11-14, kwaye uluhlu oluqhelekileyo lwe-APTT yimizuzwana engama-27-45. Ukolulwa kwe-PT ngaphezu kwemizuzwana emi-3 kunokubaluleka okukhulu kwezonyango, kwaye ukolulwa kwe-APTT ngaphezu kwemizuzwana eli-10 kunokubaluleka okukhulu kwezonyango.