Abanye abantu abane-fifth factor kaLeiden basenokungazi. Ukuba kukho naziphi na iimpawu, eyokuqala idla ngokuba yi-blood clot kwindawo ethile yomzimba. . Ngokuxhomekeke kwindawo apho i-blood clot ikhona khona, inokuba buthathaka kakhulu okanye ibe yingozi ebomini.

Iimpawu ze-Thrombosis ziquka:

•Intlungu

•Ububomvu

•Ukudumba

•Ifiva

•I-deep vein thrombosis (i-deepveinclot, i-DVT) ixhaphakile kwimilenze esezantsi eneempawu ezifanayo kodwa ukudumba okukhulu.

Amahlwili egazi angena emiphungeni aze abangele i-pulmonary embolism, nto leyo enokwenzakalisa imiphunga kwaye inokuba yingozi ebomini. Iimpawu ziquka:

•Intlungu yesifuba okanye ukungakhululeki, okuhlala kusenziwa mandundu kukuphefumla nzulu okanye ukukhohlela

•Igazi eliphuma kwigazi (Hemoptysis)

•Ubunzima bokuphefumla

•Ukunyuka kwesantya sentliziyo okanye i-arrhythmia

•Uxinzelelo lwegazi oluphantsi kakhulu, isiyezi okanye ukuquleka

•Intlungu, ukubomvu kunye nokudumba

•I-deep vein thrombosis yemilenze esezantsi Intlungu yesifuba kunye nokungonwabi

•Ubunzima bokuphefumla

•Ukufakwa kwe-pulmonary embolism

 

 I-Leiden Fifth Factor ikwanyusa umngcipheko wezinye iingxaki nezifo

•I-deep vein thrombosis: ibhekisa ekuqineni kwegazi kunye nokwenziwa kwamahlwili egazi kwimithambo, anokubonakala nakweyiphi na indawo yomzimba, kodwa ngokuqhelekileyo kumlenze omnye kuphela. Ingakumbi kwimeko yokubhabha umgama omde kunye nokuhlala umgama omde iiyure ezininzi.

•Iingxaki zokukhulelwa: Abafazi abane-Leiden's fifth factor banamathuba amabini ukuya kwamathathu okuba baphunyelwe sisisu kwi-trimester yesibini okanye yesithathu yokukhulelwa. Oku kungenzeka ngaphezu kwesinye, kwaye kwandisa umngcipheko woxinzelelo lwegazi oluphezulu ngexesha lokukhulelwa (oogqirha banokuthi yi-pre-eclampsia okanye ukwahlukana kwe-placenta ngaphambi kwexesha eludongeni lwesibeleko (okwaziwa ngokuba yi-placental abruption). I-Leiden fifth factor nayo inokubangela ukuba umntwana akhule kancinci.

•I-Pulmonary embolism: I-thrombus iyaqhekeka kwindawo yayo yokuqala ize ivumele igazi ukuba lingene emiphungeni, nto leyo enokuthintela intliziyo ekumpompeni nasekuphefumleni.