Zithini ii-Anticoagulants zegazi?

Izinto ezisetyenziswa ngamakhemikhali okanye izinto ezinokuthintela ukujiya kwegazi zibizwa ngokuba zizinto ezithintela ukujiya kwegazi, ezifana nezinto ezithintela ukujiya kwegazi (i-heparin, i-hirudin, njl.njl.), izinto ezithintela ukujiya kwegazi (i-ca2+chelating agents) (i-sodium citrate, i-potassium fluoride). Izinto ezithintela ukujiya kwegazi ezisetyenziswa rhoqo ziquka i-heparin, i-ethylenediaminetetraacetate (ityuwa ye-EDTA), i-citrate, i-oxalate, njl. Xa zisetyenziswa ngokwenene, izinto ezithintela ukujiya kwegazi kufuneka zikhethwe ngokweemfuno ezahlukeneyo ukuze kufunyanwe iziphumo ezifanelekileyo.

Inaliti yeHeparin

Inaliti yeHeparin sisithinteli-gazi esithintela ukujiya kwegazi. Isetyenziselwa ukunciphisa amandla egazi okujiya igazi kwaye incede ekuthinteleni ukwakheka kwamahlwili ayingozi emithanjeni yegazi. Eli yeza ngamanye amaxesha libizwa ngokuba liyi-blood thinner, nangona linganciphisi igazi. IHeparin ayinyibilikisi amahlwili egazi asele enziwe, kodwa inokuwathintela ukuba angabi makhulu, nto leyo enokubangela iingxaki ezinzulu ngakumbi.

I-Heparin isetyenziselwa ukuthintela okanye ukunyanga izifo ezithile zemithambo yegazi, zentliziyo nezemiphunga. I-Heparin ikwasetyenziselwa ukuthintela ukujiya kwegazi ngexesha lotyando lwentliziyo evulekileyo, utyando lwentliziyo edlulayo, i-kidney dialysis kunye notofelo-gazi. Isetyenziswa ngeedosi eziphantsi ukuthintela i-thrombosis kwabanye abaguli, ingakumbi abo kufuneka benze utyando oluthile okanye kufuneka bahlale ebhedini ixesha elide. I-Heparin ingasetyenziselwa ukuxilonga nokunyanga isifo segazi esibi esibizwa ngokuba yi-dispersed intravascular coagulation.

Ingathengwa kuphela ngomyalelo kagqirha.

Ityuwa ye-EDTC

Yikhemikhali ebopha ii-ion ezithile zesinyithi, ezifana ne-calcium, i-magnesium, i-lead, kunye ne-iron. Isetyenziselwa amayeza ukuthintela iisampuli zegazi ekuqhekekeni nasekususeni i-calcium kunye ne-lead emzimbeni. Ikwasetyenziselwa ukuthintela iintsholongwane ekubeni zenze ii-biofilms (iileya ezincinci ezinamathele kumphezulu). Yiarhente ye-chelating. Ikwabizwa ngokuba yi-ethylene diacetic acid kunye ne-ethylene diethylenediamine tetraacetic acid.

I-EDTA-K2 ecetyiswe yiKomiti yeHlabathi yeMigangatho yeHematology inomnyibiliko ophezulu kwaye isantya sokuthintela ukujiya kwegazi sikhawuleza kakhulu.