Li-anticoagulant tsa mali ke eng?

Di-reagent tsa dikhemikhale kapa dintho tse ka thibelang ho kopana ha madi di bitswa di-anticoagulant, tse kang di-anticoagulant tsa tlhaho (heparin, hirudin, jj.), di-agent tsa Ca2+chelating (sodium citrate, potassium fluoride). Di-anticoagulant tse sebediswang haholo di kenyeletsa heparin, ethylenediaminetetraacetate (letswai la EDTA), citrate, oxalate, jj. Ha e sebediswa ka nepo, di-anticoagulant di lokela ho kgethwa ho latela ditlhoko tse fapaneng ho fumana ditlamorao tse ntle.

Ente ea Heparin

Ente ea Heparin ke sethibela-mafu. E sebelisetsoa ho fokotsa bokhoni ba mali ba ho hoama le ho thusa ho thibela ho hoama ho kotsi methapong ea mali. Moriana ona ka linako tse ling o bitsoa sethibela-mafu, leha e le hantle ha o fokolise mali. Heparin ha e qhale maqeba a mali a seng a ntse a bopiloe, empa e ka a thibela ho hola, e leng se ka lebisang mathateng a tebileng le ho feta.

Heparin e sebelisetsoa ho thibela kapa ho phekola mafu a itseng a methapo ea mali, pelo le matšoafo. Heparin e boetse e sebelisetsoa ho thibela ho hoama ha mali nakong ea opereishene ea pelo e bulehileng, opereishene ea ho thibela pelo ho ea ka tšitiso ea mali, ho hloekisa liphio le tšelo ea mali. E sebelisoa ka tekanyo e tlase ho thibela thrombosis ho bakuli ba bang, haholo-holo ba lokelang ho etsoa opereishene ea mefuta e itseng kapa ba tlamehang ho lula betheng nako e telele. Heparin e ka boela ea sebelisoa ho hlahloba le ho phekola lefu le tebileng la mali le bitsoang disseminated intravascular coagulation.

E ka rekoa feela ka lengolo la ngaka.

Letswai la EDTC

Ke ntho e kopanyang di-ion tse itseng tsa tshepe, tse kang calcium, magnesium, loto le tshepe. E sebediswa ka meriana ho thibela disampole tsa madi ho hoama le ho tlosa calcium le loto mmeleng. E boetse e sebediswa ho thibela dibaktheria ho etsa di-biofilms (mealo e mesesaane e khomaretseng bokahodimo). Ke moemedi wa chelating. E boetse e bitswa ethylene diacetic acid le ethylene diethylenediamine tetraacetic acid.

EDTA-K2 e khothaletsoang ke Komiti ea Machaba ea Maemo a Hematology e na le ho qhibiliha ho hoholo ka ho fetisisa le lebelo le potlakileng la ho thibela ho ruruha ha mali.