Beijing Succeeder Technology Inc.

Ca²⁺ imagwira ntchito yofunika kwambiri pakupanga magazi, makamaka kuphatikiza zinthu izi:

1. Kutenga nawo mbali pakuyambitsa zinthu zotsekeka kwa magazi:
Zinthu zambiri zolimbitsa thupi zimafuna kuti Ca²⁺ igwire ntchito pamene ikugwira ntchito. Mwachitsanzo, poyambitsa zinthu zolimbitsa thupi IX, X, XI, XII, ndi zina zotero, Ca²⁺ imafunika kuti igwirizane ndi zinthu zolimbitsa thupi izi kuti zisinthe mawonekedwe ake ndikuwulula malo ogwirira ntchito, kuti athe kuyanjana ndi zinthu zina zolimbitsa thupi ndikuyambitsa coagulation cascade reaction.

2. Kulimbikitsa kupangika kwa ma coagulation factor complexes:
Ca²⁺ ikhoza kugwira ntchito ngati mlatho wolimbikitsa mapangidwe a ma complexes pakati pa zinthu zozungulira. Mwachitsanzo, mu njira yozungulira, Ca²⁺ imatha kulumikiza ma phospholipids omwe ali ndi mphamvu yoipa (omwe ali pamwamba pa nembanemba ya ma platelet, ndi zina zotero) ndi zinthu zozungulira Xa, V, ndi zina zotero kuti apange ma prothrombin complexes, zomwe zimafulumizitsa njira yosinthira prothrombin kukhala thrombin.

3. Kuyambitsa ndi kutulutsidwa kwa ma platelet:
Ca²⁺ ndi yofunika kwambiri pa kuyambitsa ndi kumasula ma platelet. Mitsempha yamagazi ikawonongeka, ma platelet amamatira ku gawo lowonongeka, ndipo Ca²⁺ imalowa m'ma platelet, zomwe zimapangitsa kuti pakhale zochitika zosiyanasiyana za biochemical mu ma platelet, zomwe zimapangitsa kuti zinthu zosiyanasiyana zomwe zimagwira ntchito m'ma platelet zitulutsidwe, monga adenosine diphosphate (ADP), thromboxane A₂, ndi zina zotero. Zinthuzi zimathandiziranso kusonkhana kwa ma platelet ndi magazi kuundana.

4. Kukhazikitsa ma polima a fibrin:
Pa gawo lomaliza la kugayika kwa magazi, fibrinogen imasinthidwa kukhala ma monomers a fibrin pansi pa mphamvu ya thrombin, kenako ma monomers a fibrin amalumikizidwa kuti apange ma polima okhazikika a fibrin pansi pa mphamvu ya Ca²⁺ ndi coagulation factor XIII, motero amapanga magazi olimba kuti akwaniritse cholinga cha hemostasis. Popanda Ca²⁺, ma monomers a fibrin sangalumikizidwe kukhala ma polima okhazikika a fibrin, magazi olimba sangapangidwe bwino, ndipo magazi sangalumikizidwe bwino.

Beijing Succeeder Technology Inc. (Nambala ya stock: 688338), yomwe idakhazikitsidwa mu 2003 ndipo idalembedwa kuyambira 2020, ndi kampani yotsogola pakuwunika matenda a coagulation. Timagwira ntchito kwambiri ndi ma automated coagulation analyzers ndi reagents, ESR/HCT analyzers, ndi hemorheology analyzers. Zogulitsa zathu zili ndi satifiketi motsatira ISO 13485 ndi CE, ndipo timatumikira ogwiritsa ntchito oposa 10,000 padziko lonse lapansi.

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