Kusiyana pakati pa thromboplastin ndi thrombin kuli m'malingaliro osiyanasiyana, zotsatira zake, ndi mphamvu za mankhwala. Nthawi zambiri, iyenera kugwiritsidwa ntchito motsatira malangizo a dokotala. Ngati pali zovuta zilizonse, monga ziwengo, kutentha thupi pang'ono, ndi zina zotero, muyenera kusiya kumwa mankhwala nthawi yomweyo ndikupita ku dipatimenti ya hematology kuti mukalandire chithandizo.

1. Malingaliro osiyanasiyana:
Thromboplastin, yomwe imadziwikanso kuti thrombin, ndi chinthu chomwe chingayambitse prothrombin kukhala thrombin. Thrombin, yomwe imadziwikanso kuti fibrinase, ndi serine protease yomwe ndi yoyera mpaka imvi youma kapena ufa. Ndi enzyme yofunika kwambiri mu njira yolumikizirana;

2. Zotsatira zosiyanasiyana:
Thromboplastin imatha kufulumizitsa mapangidwe a magazi oundana pamwamba pa chotupacho mwa kuyambitsa kusintha kwa prothrombin kukhala thrombin, motero kukwaniritsa cholinga cha hemostasis yofulumira. Thrombin nthawi zambiri imatha kugwira ntchito mwachindunji pa gawo lomaliza la njira yolumikizirana, kusintha fibrinogen mu plasma kukhala fibrin yosasungunuka. Pambuyo pogwiritsidwa ntchito m'deralo, imagwira ntchito pamagazi pamwamba pa chotupacho, zomwe zimathandiza kuti magazi oundana apangidwe mwachangu komanso mokhazikika. Nthawi zambiri imagwiritsidwa ntchito kuletsa kutuluka magazi m'mitsempha ndi m'mitsempha, ndipo ingagwiritsidwenso ntchito ngati chowonjezera pakhungu ndi minofu yoikidwa;

3. Mitundu yosiyanasiyana ya mankhwala:
Thrombin ili ndi mankhwala amodzi okha, ufa wosabalalitsidwa wa lyophilized, womwe ndi woletsedwa kwa odwala omwe ali ndi vuto la thrombin. Ndipo thrombin ili ndi jakisoni wokha, womwe ungangobayidwa mu intramuscularly, osati kudzera m'mitsempha, kuti apewe thrombosis.

Mu moyo watsiku ndi tsiku, muyenera kupewa kumwa mankhwala mosasamala nokha, ndipo mankhwala onse ayenera kugwiritsidwa ntchito motsogozedwa ndi madokotala aluso.