Nazi zina mwa ma coagulants ofala komanso makhalidwe awo:

Vitamini K
Njira yogwirira ntchito: Imagwira ntchito popanga zinthu zolimbitsa thupi II, VII, IX, ndi X, zomwe zimapangitsa kuti zinthu zolimbitsa thupizi zizigwira ntchito, motero imalimbikitsa kulimba kwa magazi.
Zinthu zomwe zingagwiritsidwe ntchito: Amagwiritsidwa ntchito kwambiri pa matenda otuluka magazi chifukwa cha kusowa kwa vitamini K, monga matenda otuluka magazi a makanda, kusowa kwa vitamini K chifukwa cha kusayamwa bwino kwa m'mimba, ndi zina zotero. Angagwiritsidwenso ntchito pa matenda otuluka magazi chifukwa cha kusakwanira kwa vitamini K m'thupi chifukwa chogwiritsa ntchito mankhwala opha tizilombo toyambitsa matenda kwa nthawi yayitali.
Ubwino: Ndi mankhwala olimbikitsa kugawanika kwa magazi m'thupi, omwe amathandiza kwambiri pa vuto la kugawanika kwa magazi m'thupi chifukwa cha kusowa kwa vitamini K ndipo ndi otetezeka kwambiri.
Zoyipa: Zimatenga nthawi yayitali kuti zigwire ntchito, ndipo zotsatira za hemostatic pa kutuluka magazi ambiri sizingachitike panthawi yake.

Thrombin
Njira yogwirira ntchito: Imagwira ntchito mwachindunji pa fibrinogen m'magazi, n’kuisintha kukhala fibrin, kenako n’kupanga magazi kuundana kuti ikwaniritse cholinga cha hemostasis.
Zochitika Zoyenera: Ingagwiritsidwe ntchito pochiza magazi m'malo olumikizirana mafupa, monga kutuluka magazi kuchokera ku mabala ochitidwa opaleshoni, mabala ovulala, ndi zina zotero; ingagwiritsidwenso ntchito pochiza magazi m'mimba, monga kumwa mankhwala olowetsedwa m'kamwa kapena m'malo olumikizirana mafupa pochiza magazi m'mimba ndi m'matumbo, ndi zina zotero.
Ubwino: Kuthamanga kwa magazi mwachangu, kumatha kutseka magazi mwachangu ndikuchepetsa kutuluka magazi akagwiritsidwa ntchito m'deralo.
Zoyipa: Iyenera kupakidwa mwachindunji pamalo omwe magazi amatuluka, siiyenera kubayidwa kudzera m'mitsempha, apo ayi ingayambitse magazi kuundana, zomwe zimayambitsa thrombosis yayikulu komanso zotsatira zina zoyipa.

Ethylphenolsulfonamide
Njira yogwirira ntchito: Imatha kukulitsa kukana kwa capillary, kuchepetsa kutseguka kwa capillary, kulimbikitsa kusonkhana kwa ma platelet ndikutulutsa zinthu zogwira ntchito, motero kuchepetsa nthawi yolumikizirana ndikupeza zotsatira za hemostatic.
Zochitika Zofunikira: Amagwiritsidwa ntchito kwambiri popewa ndikuchiza kutuluka magazi chifukwa cha kutuluka magazi chifukwa cha opaleshoni, thrombocytopenic purpura kapena allergic purpura.
Ubwino: Kuchepa kwa poizoni, zotsatira zoyipa zochepa, komanso kotetezeka.
Zoyipa: Mphamvu ya hemostatic imakhala yofooka ikagwiritsidwa ntchito yokha, ndipo nthawi zambiri imagwiritsidwa ntchito limodzi ndi mankhwala ena a hemostatic.

Tranexamic acid
Njira yogwirira ntchito: Imakwaniritsa cholinga cha hemostasis mwa kuletsa kuyambika kwa dongosolo la fibrinolytic. Imatha kuletsa mopikisana kumangirira kwa plasminogen ku fibrin, kotero kuti plasminogen singasinthidwe kukhala plasmin, motero imaletsa kusungunuka kwa fibrin ndikuchita gawo la hemostatic.
Mikhalidwe yogwiritsira ntchito: Imagwira ntchito pa matenda osiyanasiyana otuluka magazi chifukwa cha hyperfibrinolysis, monga kutuluka magazi m'thupi la amayi, kutuluka magazi m'maselo a prostate, kutuluka magazi m'chiwindi, ndi zina zotero.
Ubwino: Kuchuluka kwa magazi m'thupi, makamaka pa kutuluka magazi chifukwa cha kuchuluka kwa ntchito ya fibrinolytic.
Zoyipa: Zingayambitse thrombosis, ndipo ziyenera kugwiritsidwa ntchito mosamala kwa odwala omwe ali ndi vuto la thrombosis kapena mbiri ya thrombosis.

Pakugwiritsa ntchito kwenikweni, ndikofunikira kuganizira mokwanira ndikusankha ma coagulants oyenera kutengera momwe wodwalayo alili, chifukwa chake ndi komwe magazi amachokera, momwe thupi lake lilili ndi zinthu zina. Nthawi zina, ndikofunikira kugwiritsa ntchito ma coagulants angapo pamodzi kuti mupeze zotsatira zabwino kwambiri za hemostatic. Nthawi yomweyo, mukamagwiritsa ntchito ma coagulants, muyenera kutsatira malangizo a dokotala mosamala ndikuyang'anitsitsa momwe wodwalayo amachitira kuti muwonetsetse kuti ali otetezeka komanso ogwira ntchito.