Ihe kpatara thrombosis nwere ike ịbụ ihe ndị a:

1. O nwere ike ịbụ na ọ metụtara mmerụ ahụ endothelium, a na-akpụkwa thrombus na endothelium vascular. Ọtụtụ mgbe, n'ihi ọtụtụ ihe kpatara endothelium, dịka kemịkalụ ma ọ bụ ọgwụ ma ọ bụ endotoxin, ma ọ bụ mmerụ ahụ endothelial nke atheromatous plaque kpatara, wdg, endothelial thrombus na-etolite mgbe mmerụ ahụ gasịrị;

2. Dịka ọmụmaatụ, mkpụkọ ọbara, mmụba nke ọrụ platelet, ma ọ bụ enweghị usoro mkpụkọ ọbara nwere ike ibute mmepe nke thrombus;

3. Ọbara na-agbada ma ọ bụ na-ebelata olu ọbara, mmụba ọbara na-abawanye, nke nwekwara ike ibute mmepe nke thrombus, yabụ enwere ọtụtụ ihe kpatara e ji guzobe thrombus;

4. Na mgbakwunye na ihe ndị a kpọtụrụ aha n'elu, ihe ndị na-akpata thrombosis gụnyekwara mmụba nke ọrụ nke sistemu fibrinolytic. Na mgbakwunye, enwere mmụba na ọnụọgụ platelet, nke nwere ike ibute ọrịa thrombotic, yabụ enwere ọtụtụ ihe kpatara ya.