Hauv cov lus kho mob, "coagulation" yog ib qho txheej txheem nyuaj ntawm lub cev, uas yog hais txog ntau yam kev hloov pauv uas cov ntshav hloov los ntawm cov kua mus rau cov khoom khov zoo li gel. Lub hom phiaj tseem ceeb yog kom tsis txhob los ntshav thiab tiv thaiv kom tsis txhob poob ntshav ntau dhau. Cov hauv qab no yog cov lus piav qhia ntxaws ntxaws txog cov yam ntxwv ntawm cov coagulation, cov txheej txheem coagulation thiab cov txheej txheem coagulation tsis zoo:
1-Cov yam ntxwv ua rau cov ntshav khov: Muaj ntau yam ua rau cov ntshav khov hauv cov ntshav, xws li cov yam ntxwv I (fibrinogen), yam ntxwv II (prothrombin), yam ntxwv V, yam ntxwv VII, yam ntxwv VIII, yam ntxwv IX, yam ntxwv X, yam ntxwv XI, yam ntxwv XII, thiab lwm yam. Feem ntau ntawm lawv tau tsim ua ke hauv lub siab. Cov yam ntxwv ua rau cov ntshav khov no ua lub luag haujlwm tseem ceeb hauv cov txheej txheem ua rau cov ntshav khov, thiab los ntawm ntau yam kev ua haujlwm thiab kev sib cuam tshuam, cov ntshav thaum kawg tau khov.
2-Txheej txheem coagulation: Nws tuaj yeem muab faib ua txoj kev coagulation intrinsic thiab txoj kev coagulation exogenous. Ob txoj kev thaum kawg sib sau ua ke rau txoj kev coagulation sib xws los tsim thrombin, uas tig mus hloov fibrinogen mus rau hauv fibrin los tsim cov ntshav txhaws.
(1) Txoj kev coagulation intrinsic: Thaum cov hlab ntsha endothelium raug puas tsuaj thiab cov ntshav los rau hauv kev sib cuag nrog cov subendothelial collagen fibers, factor XII raug qhib, pib txoj kev coagulation intrinsic. Factor XI, factor IX, factor X, thiab lwm yam ces raug qhib ua ntu zus, thiab thaum kawg, ntawm qhov chaw phospholipid uas muab los ntawm platelets, factor X, factor V, calcium ions thiab phospholipids ua ke tsim prothrombin activator.
(2) Txoj kev coagulation sab nraud: Nws pib los ntawm kev tso tawm ntawm cov ntaub so ntswg (TF) los ntawm kev puas tsuaj ntawm cov ntaub so ntswg. TF sib xyaw nrog factor VII los tsim ib qho TF-VII complex, uas ua rau factor X ua haujlwm thiab tom qab ntawd tsim cov prothrombin activator. Txoj kev coagulation sab nraud sai dua li txoj kev coagulation sab hauv thiab tuaj yeem ua rau cov ntshav coagulate hauv lub sijhawm luv dua.
(3) Txoj kev coagulation feem ntau: Tom qab tsim cov prothrombin activator, prothrombin raug qhib rau thrombin. Thrombin yog ib qho tseem ceeb coagulation factor uas catalyzes kev hloov pauv ntawm fibrinogen mus rau hauv fibrin monomers. Nyob rau hauv qhov kev ua ntawm factor XIII thiab calcium ions, fibrin monomers cross-link los tsim cov fibrin polymers ruaj khov. Cov fibrin polymers no yog interwoven rau hauv ib lub network, encapring cov qe ntshav los tsim cov ntshav clots thiab ua tiav cov txheej txheem coagulation.
3-Txoj kev coagulation tsis zoo: suav nrog hypercoagulability thiab coagulation teeb meem.
(1) Hypercoagulability: Lub cev nyob rau hauv lub xeev hypercoagulable thiab yooj yim thrombosis. Piv txwv li, thaum muaj kev raug mob hnyav, phais loj, qog nqaij hlav phem, thiab lwm yam, cov haujlwm ntawm cov coagulation factors thiab platelets hauv cov ntshav nce ntxiv, thiab cov ntshav viscosity nce ntxiv, uas tuaj yeem yooj yim ua rau thrombosis, uas yuav ua rau muaj cov kab mob loj xws li pulmonary embolism, cerebral infarction, myocardial infarction, thiab lwm yam, thiab ua rau lub neej muaj kev phom sij.
(2) Kev tsis sib haum xeeb ntawm cov ntshav coagulation: hais txog qhov tsis muaj lossis ua haujlwm tsis zoo ntawm qee yam coagulation factors hauv cov txheej txheem coagulation ntshav, uas ua rau muaj kev nce ntxiv ntawm kev los ntshav. Cov laj thawj feem ntau suav nrog kev tsis txaus ntawm cov coagulation factor, xws li hemophilia A (factor VIII deficiency) thiab hemophilia B (factor IX deficiency); vitamin K deficiency, uas cuam tshuam rau kev tsim cov factors II, VII, IX, thiab X; kab mob siab, uas ua rau kev tsim cov coagulation factors tsawg dua; thiab kev siv cov tshuaj anticoagulants, xws li warfarin thiab heparin, uas cuam tshuam rau cov txheej txheem coagulation.
Kev coagulation ua lub luag haujlwm tseem ceeb hauv kev tswj hwm kev ua haujlwm ntawm lub cev tib neeg. Txhua qhov tsis zoo ntawm kev ua haujlwm coagulation yuav muaj kev cuam tshuam loj rau kev noj qab haus huv. Hauv kev kho mob, ntau yam kev kuaj coagulation, xws li lub sijhawm prothrombin (PT), lub sijhawm ua haujlwm ib nrab thromboplastin (APTT), kev txiav txim siab fibrinogen, thiab lwm yam, feem ntau yog siv los ntsuas tus neeg mob txoj haujlwm coagulation, kom paub thiab kho cov kab mob ntsig txog coagulation raws sijhawm.
Beijing Succeeder Technology Inc. (Tus lej khoom lag luam: 688338), tau tsim muaj xyoo 2003 thiab tau teev npe txij li xyoo 2020, yog lub tuam txhab tsim khoom lag luam hauv kev kuaj mob coagulation. Peb tshwj xeeb hauv kev siv tshuab coagulation analyzers thiab reagents, ESR/HCT analyzers, thiab hemorheology analyzers. Peb cov khoom tau ntawv pov thawj raws li ISO 13485 thiab CE, thiab peb pabcuam ntau dua 10,000 tus neeg siv thoob ntiaj teb.
Kev Taw Qhia Txog Analyzer
Lub tshuab ntsuas ntshav khov kho tsis siv neeg SF-9200 (https://www.succeeder.com/fully-automated-coagulation-analyzer-sf-9200-product) siv tau rau kev kuaj mob thiab kev kuaj mob ua ntej phais. Cov tsev kho mob thiab cov kws tshawb fawb kho mob kuj siv tau SF-9200. Uas siv cov txheej txheem coagulation thiab immunoturbidimetry, chromogenic los kuaj cov ntshav khov. Lub cuab yeej qhia tau tias tus nqi ntsuas ntshav khov yog lub sijhawm khov (hauv vib nas this). Yog tias cov khoom kuaj tau calibrated los ntawm calibration plasma, nws kuj tseem tuaj yeem tso saib lwm cov txiaj ntsig cuam tshuam.
Cov khoom no yog ua los ntawm cov khoom siv kuaj mob uas txav tau, cov khoom ntxuav, cov khoom siv cuvettes uas txav tau, cov khoom cua sov thiab txias, cov khoom kuaj, cov khoom ua haujlwm uas tso tawm, LIS interface (siv rau lub tshuab luam ntawv thiab hnub hloov mus rau Computer).
Cov neeg ua haujlwm txawj ntse thiab cov kws tshuaj ntsuam xyuas uas muaj kev paub dhau los thiab kev tswj hwm zoo thiab nruj yog qhov lav ntawm kev tsim khoom ntawm SF-9200 thiab zoo. Peb lav txhua lub cuab yeej tshuaj xyuas thiab sim nruj me ntsis. SF-9200 ua tau raws li tus qauv hauv tebchaws Suav, tus qauv kev lag luam, tus qauv lag luam thiab tus qauv IEC.
SF-9200
Kev Tshuaj Xyuas Kev Sib Koom Tes Tag Nrho
Cov Lus Qhia Tshwj Xeeb
Kev Ntsuas: Kev ntsuas ntshav txhaws raws li viscosity (mechanical) clotting, Chromogenic thiab Immunoassays.
Cov Qauv: 4 qhov probes ntawm cov caj npab sib cais, lub hau-tho xaiv tau.
Kev Ntsuas Channel: 20
Kev Tsim Kab: 30
Txoj Haujlwm Reagent: 60 qhov tig thiab qaij, nyeem barcode sab hauv thiab thauj khoom tsis siv neeg, saib xyuas qhov ntim ntawm cov reagent,
kev hloov pauv ntawm ntau lub raj mis, kev ua haujlwm txias, kev sib tov reagent tsis sib cuag.
Qhov Chaw Qauv: 190 thiab nthuav dav, tsis siv neeg thauj khoom, saib xyuas qhov ntim ntawm cov qauv, lub raj tig tsis siv neeg thiab nyeem barcode, 8 qhov chaw STAT sib cais, xaiv tau qhov tho qhov hau, txhawb nqa LAS.
Kev Khaws Cov Ntaub Ntawv: Kev khaws cov txiaj ntsig tsis siv neeg, cov ntaub ntawv tswj hwm, cov ntaub ntawv calibration thiab lawv cov duab.
Kev Saib Xyuas Txawj Ntse: Ntawm qhov probe tiv thaiv kev sib tsoo, cuvette ntes, kua siab, probe thaiv thiab ua haujlwm.
Cov txiaj ntsig tuaj yeem tshawb nrhiav los ntawm hnub tim, tus lej qauv lossis lwm yam xwm txheej, thiab tuaj yeem raug tshem tawm, pom zoo, uploaded, exported, luam tawm, thiab tuaj yeem suav los ntawm qhov ntau ntawm kev sim.
Cov Txheej Txheem Ntsuas: Cov txheej txheem ntsuas tau, cov kev ntsuas ntsuas thiab cov txiaj ntsig ntawm chav ntsuas tau, cov kev ntsuas ntsuas suav nrog kev tshuaj xyuas, qhov tshwm sim, kev rov ua kom yaj thiab cov kev ntsuas rov sim.
Kev Ua Haujlwm: PT ≥ 415 T/H, D-Dimer ≥ 205 T/H.
Qhov Ntsuas Ntsuas: 1500 * 835 * 1400 (L * W * H, hli)
Qhov Hnyav ntawm Cov Cuab Yeej: 220 kg
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