Ke hoʻomaopopo nei i ka nui o ke koko coagulation: ka pae maʻamau a me ke koʻikoʻi olakino

Ma ke kahua o ke olakino lapaʻau, ʻo ka hana coagulation koko kahi loulou koʻikoʻi i ka mālama ʻana i ke kūlana physiological maʻamau o ke kino kanaka. ʻO ka nui o ke coagulation koko, i ana pinepine ʻia e nā ʻōkuhi e pili ana i ka coagulation, he kuleana koʻikoʻi ia i ka hoʻoholo ʻana i ke kūlana olakino o ke kino kanaka. No laila, he aha ka nui maʻamau o ke coagulation koko? Pili kēia pilikia i ka ʻike a me ka mālama ʻana i nā maʻi he nui, a ua huki pū ʻia ka nui o ka nānā ʻana mai nā loea lapaʻau a me ka lehulehu.

Ma ke ʻano laulā, ʻo nā hōʻailona hoʻāʻo hana coagulation i hoʻohana pinepine ʻia i ka hana lapaʻau e komo pū me ka manawa prothrombin (PT), ka manawa thromboplastin hapa i hoʻāla ʻia (APTT), ka manawa thrombin (TT) a me ka fibrinogen (FIB).
ʻO nā pae maʻamau o kēia mau hōʻailona:
ʻO ka manawa Prothrombin (PT) maʻamau ma waena o 10 a me 14 kekona, a he mea koʻikoʻi ia ma ke ʻano lapaʻau inā ʻoi aku ia ma mua o 3 kekona ma mua o ka mana maʻamau;
ʻO ka pae maʻamau o ka manawa thromboplastin hapa i hoʻāla ʻia (APTT) he 25 a 37 kekona, a inā ʻoi aku ia ma mua o ka mana maʻamau ma mua o 10 kekona, pono e lawe koʻikoʻi ʻia;
ʻO ka manawa thrombin maʻamau (TT) he 12 a 16 kekona, a ʻo ka ʻoi aku ma mua o 3 kekona ma mua o ka mana maʻamau e hōʻike ana he mau mea ʻē paha;
ʻO ka nui maʻamau o ka fibrinogen (FIB) ma waena o 2 a me 4g/L.

Eia nō naʻe, pono e hoʻomaopopo ʻia ma muli o nā ʻokoʻa o nā ʻano nānā, nā reagents a me nā mea hana i hoʻohana ʻia e nā haukapila like ʻole, ʻokoʻa iki paha ka pae maʻamau o nā waiwai coagulation. No laila, pono e hoʻokumu ʻia ka pae kuhikuhi maʻamau ma ke ʻano hōʻike o ka haukapila kahi e mālama ʻia ai ka mea maʻi.

ʻO ka nui o ke kōʻana koko maʻamau ʻole e pili pinepine ana i nā ʻano maʻi like ʻole. Ke kiʻekiʻe loa ka nui o ke kōʻana koko, hiki ke kumu o nā maʻi e like me ka thrombocytosis, polycythemia vera, a me ka disseminated intravascular coagulation, ka mea e hoʻonui ai i ke kōʻana koko a pēlā e hoʻonui ai i ka pilikia o ka thrombosis. Eia kekahi, ʻo kekahi mau lāʻau lapaʻau e like me nā anticoagulants (heparin, warfarin), nā lāʻau antiplatelet (aspirin, clopidogrel), nā lāʻau chemotherapy, a me nā lāʻau lapaʻau e like me ka hemodialysis a me ka extracorporeal membrane oxygenation (ECMO) hiki ke hoʻopilikia i ka hana coagulation, e hopena ana i ka coagulation nui. I ka ʻaoʻao ʻē aʻe, hiki ke hana ʻia ka hana coagulation maʻamau ʻole e ka hemahema o ka mea hoʻoilina coagulation, ka hemahema o ka vitamin K, thrombocytopenia, ka hoʻohana nui ʻana i nā anticoagulants, a me nā maʻi ʻai mea hoʻohuihui koko. Hiki i kēia mau kūlana ke alakaʻi i nā maʻi coagulation koko a he maʻalahi ke kahe koko.

No ka lehulehu, he mea nui loa ia e hoʻomaopopo i ka pae maʻamau o ka nui o ke koko a me ka ʻike pili i ka hana coagulation ʻano ʻē. Inā ʻike ʻia ka nui o ke koko ʻano ʻē i ka wā o ka hoʻokolokolo kino a i ʻole ka mālama ʻana i ka lāʻau lapaʻau, pono e kūkākūkā me ke kauka i ka manawa kūpono e wehewehe i ke kumu a lawe i nā hana lapaʻau kūpono. I ka manawa like, ʻo nā hoʻokolokolo kino maʻamau a me ka mālama ʻana i kahi nohona olakino he mea maikaʻi nō hoʻi no ka mālama ʻana i ka hana coagulation maʻamau.

Ua komo nui ʻo Beijing Succeeder Technology Inc. (code stock: 688338) i ke kahua o ka ʻike ʻana i ka coagulation mai kona hoʻokumu ʻia ʻana i ka makahiki 2003, a ua kūpaʻa ʻo ia e lilo i alakaʻi ma kēia kahua. Me ke keʻena nui ma Beijing, he hui R&D, hana a kūʻai aku ikaika ka hui, e kālele ana i ka hana hou a me ka hoʻohana ʻana i ka ʻenehana ʻike thrombosis a me hemostasis.

Me kona ikaika loea koʻikoʻi, ua lanakila ʻo Succeeder i 45 mau palapala sila i ʻae ʻia, me 14 mau palapala sila i hana ʻia, 16 mau palapala sila hoʻohālike pono a me 15 mau palapala sila hoʻolālā. Loaʻa i ka hui he 32 mau palapala hoʻopaʻa inoa huahana lāʻau lapaʻau Papa II, 3 mau palapala hoʻopaʻa inoa Papa I, a me ka palapala hōʻoia EU CE no 14 mau huahana, a ua hala i ka palapala hōʻoia ʻōnaehana hoʻokele maikaʻi ISO 13485 e hōʻoia i ka maikaʻi a me ke kūpaʻa o ka maikaʻi o ka huahana.

ʻAʻole wale ʻo Succeeder kahi ʻoihana koʻikoʻi o ka Beijing Biomedicine Industry Leapfrog Development Project (G20), akā ua pae maikaʻi ʻo ia ma ka Science and Technology Innovation Board i ka makahiki 2020, e hoʻokō ana i ka hoʻomohala leapfrog o ka ʻoihana. I kēia manawa, ua kūkulu ka ʻoihana i kahi pūnaewele kūʻai aku ma ka ʻāina holoʻokoʻa e uhi ana i nā haneli o nā ʻelele a me nā keʻena. Kūʻai maikaʻi ʻia kāna huahana ma ka hapa nui o ka ʻāina. Ke hoʻonui nei hoʻi i nā mākeke ma waho a ke hoʻomaikaʻi mau nei i kona hoʻokūkū honua.