Aia nā ʻōnaehana coagulation a me nā anticoagulation i loko o ke koko kanaka. Ma lalo o nā kūlana maʻamau, mālama nā mea ʻelua i kahi kaulike dynamic e hōʻoia i ke kahe maʻamau o ke koko i loko o nā kīʻaha koko, a ʻaʻole e hana i ka thrombus. I ke ʻano o ke koko haʻahaʻa, nele i ka wai inu, a me nā mea ʻē aʻe, e lohi ke kahe o ke koko, e paʻa a viscous ke koko, e hyperactive ka hana coagulation a i ʻole e nāwaliwali ka hana anticoagulation, ka mea e uhaki ai i kēia kaulike a hoʻolilo i nā kānaka i loko o kahi "thrombotic state". Hiki ke loaʻa ka thrombosis ma nā wahi āpau o nā kīʻaha koko. Ke kahe nei ka thrombus me ke koko i loko o nā kīʻaha koko. Inā noho ia i loko o nā aʻa lolo a ālai i ke kahe koko maʻamau o nā aʻa lolo, he thrombosis lolo ia, ka mea e hoʻoulu ai i ka stroke ischemic. Hiki i nā kīʻaha coronary o ka puʻuwai ke hoʻoulu i ka myocardial infarction, eia kekahi, ka thrombosis arterial ʻaoʻao haʻahaʻa, ka thrombosis venous hohonu o nā ʻaoʻao haʻahaʻa, a me ka embolism pulmonary.

ʻO ka Thrombosis, ʻo ka hapa nui o lākou e loaʻa nā hōʻailona koʻikoʻi i ka hoʻomaka mua ʻana, e like me ka hemiplegia a me ka aphasia ma muli o ka infarction cerebral; colic pcordial koʻikoʻi i ka myocardial infarction; ʻeha nui o ka umauma, dyspnea, hemoptysis i hoʻokumu ʻia e ka infarction pulmonary; Hiki iā ia ke hōʻeha i nā wāwae, a i ʻole kahi manaʻo anu a me ka claudication intermittent. ʻO ka puʻuwai koʻikoʻi loa, ka infarction cerebral a me ka infarction pulmonary hiki ke hana i ka make koke. Akā i kekahi manawa ʻaʻohe hōʻailona maopopo, e like me ka thrombosis vein hohonu maʻamau o ka ʻaoʻao haʻahaʻa, ʻo ke keiki bipi wale nō ka ʻeha a me ka ʻoluʻolu ʻole. Manaʻo ka nui o nā maʻi ma muli o ka luhi a i ʻole ke anu, akā ʻaʻole lākou e lawe koʻikoʻi, no laila he mea maʻalahi ke haʻalele i ka manawa maikaʻi loa no ka mālama ʻana. He mea minamina loa ia he nui nā kauka i maʻalahi i ka misdiagnosis. Ke hana ʻia ka edema maʻamau o ka ʻaoʻao haʻahaʻa, ʻaʻole ia e lawe wale i nā pilikia i ka mālama ʻana, akā e waiho maʻalahi hoʻi i nā sequelae.