ʻO ka maʻamau, ʻo ka fibrinogen kahi kumu koko koko.

ʻO ke kumu coagulation kahi mea coagulation i loko o ka plasma, hiki ke komo i ke kaʻina hana o ke coagulation koko a me ka hemostasis. He mea nui ia i loko o ke kino kanaka e komo ana i ke coagulation koko a me ka hemostasis. ʻO Fibrinogen kahi mea coagulation koko i hana ʻia e ke akepaʻa, nona ke kuleana koʻikoʻi i ke kaʻina hana coagulation koko a komo i ke kaʻina hana hemostasis o ke kino. He kuleana koʻikoʻi ko Fibrinogen i ke kaʻina hana coagulation koko, a ʻo ka hoʻonui a me ka emi ʻana o ka fibrinogen e alakaʻi i nā maʻi e like me ke kahe koko a i ʻole ka thrombus i loko o ke kino kanaka.

Inā ʻaʻole kūpono ke kiʻekiʻe o ka fibrinogen, hiki ke alakaʻi i ka loaʻa ʻana o nā maʻi thrombotic, e like me ka myocardial infarction a me ka cerebral infarction. No laila, inā ʻike ʻoe he ʻano ʻē kou pae fibrinogen, pono ʻoe e hele i ka haukapila no ka hoʻokolokolo a me ka mālama ʻana i ka manawa kūpono e pale aku ai i nā pilikia koʻikoʻi. I ka manawa like, e makaʻala i ka mālama ʻana i nā ʻano nohona maikaʻi, e like me ka ʻai māmā, ka hoʻoikaika kino kūpono, a me nā mea ʻē aʻe, e pale aku i ka loaʻa ʻana o nā clots koko. I ka hopena, he mea nui ka fibrinogen no ka coagulation e komo ana i ke kaʻina hana coagulation a he kuleana koʻikoʻi hoʻi i ka hemostasis a me ka mālama ʻana i ke olakino kanaka. I ke ola o kēlā me kēia lā, e makaʻala i ka mālama ʻana i nā ʻano nohona maikaʻi e pale aku ai i ka loaʻa ʻana o nā clots koko.