He aha nā Anticoagulants koko?

ʻO nā mea hana kemika a i ʻole nā ​​​​mea e hiki ke pale i ke kāpili ʻana o ke koko ua kapa ʻia he anticoagulants, e like me nā anticoagulants kūlohelohe (heparin, hirudin, etc.), Ca2+ chelating agents (sodium citrate, potassium fluoride). ʻO nā anticoagulants i hoʻohana pinepine ʻia e komo pū me ka heparin, ethylenediaminetetraacetate (paʻakai EDTA), citrate, oxalate, etc. I ka hoʻohana pono ʻana, pono e koho ʻia nā anticoagulants e like me nā pono like ʻole e loaʻa ai nā hopena kūpono.

ʻO ka inikini Heparin

He anticoagulant ka inikini Heparin. Hoʻohana ʻia ia e hōʻemi i ka hiki ke koko ke kāpili a kōkua i ka pale ʻana i nā clots ʻino mai ka hana ʻana i loko o nā kīʻaha koko. Ua kapa ʻia kēia lāʻau lapaʻau i kekahi manawa he mea hoʻokahe koko, ʻoiai ʻaʻole ia e hoʻoheheʻe maoli i ke koko. ʻAʻole hoʻoheheʻe ʻo Heparin i nā clots koko i hana mua ʻia, akā hiki iā ia ke pale iā lākou mai ka nui ʻana, hiki ke alakaʻi i nā pilikia koʻikoʻi.

Hoʻohana ʻia ʻo Heparin e pale aku a mālama paha i kekahi mau maʻi vascular, puʻuwai a me nā māmā. Hoʻohana pū ʻia ʻo Heparin e pale aku i ke kāpili ʻana o ke koko i ka wā o ke ʻoki puʻuwai hāmama, ke ʻoki bypass puʻuwai, ka dialysis kidney a me ke kahe koko. Hoʻohana ʻia ia ma nā dosis haʻahaʻa e pale aku i ka thrombosis i kekahi mau maʻi, ʻoiai ka poʻe e pono e hana i kekahi mau ʻano ʻoki a i ʻole e noho ma kahi moe no ka manawa lōʻihi. Hiki ke hoʻohana ʻia ʻo Heparin e ʻike a mālama i kahi maʻi koko koʻikoʻi i kapa ʻia ʻo disseminated intravascular coagulation.

Hiki ke kūʻai ʻia ma ke kauoha a ke kauka wale nō.

Paʻakai EDTC

He mea kemika e hoʻopaʻa ai i kekahi mau iona metala, e like me ka calcium, magnesium, kēpau, a me ka hao. Hoʻohana ʻia ia i mea lapaʻau e pale ai i nā hāpana koko mai ka hoʻopili ʻana a e wehe i ka calcium a me ke kēpau mai ke kino. Hoʻohana ʻia hoʻi e pale i ka bacteria mai ka hana ʻana i nā biofilms (nā papa lahilahi i hoʻopili ʻia i ka ʻili). He mea chelating ia. Ua kapa ʻia hoʻi ʻo ethylene diacetic acid a me ethylene diethylenediamine tetraacetic acid.

ʻO ka EDTA-K2 i ʻōlelo ʻia e ke Komite Hoʻohālikelike Hematology International ka mea solubility kiʻekiʻe loa a me ka wikiwiki anticoagulation wikiwiki loa.